4-(4-Chloro-phenyl)-1-(4-fluoro-phenyl)-1H-imidazole-2-thiol
TL;DR: 4-(4-Chloro-phenyl)-1-(4-fluoro-phenyl)-1H-imidazole-2-thiol (CAS 440119-35-7) is a chemical compound with molecular formula C15H10ClFN2S and molecular weight 304.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-(4-chlorophenyl)-3-(4-fluorophenyl)-1H-imidazole-2-thione
Also Known As: 4-(4-chlorophenyl)-1-(4-fluorophenyl)-1H-imidazole-2-thiol, 4-(4-Chloro-phenyl)-1-(4-fluoro-phenyl)-1H-imidazole-2-thiol, 5-(4-chlorophenyl)-3-(4-fluorophenyl)-1H-imidazole-2-thione, 4-(4-CHLOROPHENYL)-1-(4-FLUOROPHENYL)-2,3-DIHYDRO-1H-IMIDAZOLE-2-THIONE
| Molecular Formula | C15H10ClFN2S |
|---|---|
| Molecular Weight | 304.02 g/mol |
| LogP | 4.99439 |
| Topological Polar Surface Area | 20.72 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 2 |
| Exact Mass | 304.0237 |
| Heavy Atoms | 20 |
| Complexity | 787.9909 |
Chemical Identifiers
| CAS Number | 440119-35-7 |
|---|---|
| SMILES | C1=CC(=CC=C1C2=CN(C(=S)N2)C3=CC=C(C=C3)F)Cl |
Product Overview
4-(4-Chloro-phenyl)-1-(4-fluoro-phenyl)-1H-imidazole-2-thiol (CAS 440119-35-7), with molecular formula C15H10ClFN2S and molecular weight 304.02 g/mol. IUPAC: 5-(4-chlorophenyl)-3-(4-fluorophenyl)-1H-imidazole-2-thione.
Chemical Property Profile of 4-(4-Chloro-phenyl)-1-(4-fluoro-phenyl)-1H-imidazole-2-thiol
Property Insights of 4-(4-Chloro-phenyl)-1-(4-fluoro-phenyl)-1H-imidazole-2-thiol
The XLogP value of 4.99439 indicates that 4-(4-Chloro-phenyl)-1-(4-fluoro-phenyl)-1H-imidazole-2-thiol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 20.72 Ų, 4-(4-Chloro-phenyl)-1-(4-fluoro-phenyl)-1H-imidazole-2-thiol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-(4-Chloro-phenyl)-1-(4-fluoro-phenyl)-1H-imidazole-2-thiol has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(4-Chloro-phenyl)-1-(4-fluoro-phenyl)-1H-imidazole-2-thiol?
The CAS number of 4-(4-Chloro-phenyl)-1-(4-fluoro-phenyl)-1H-imidazole-2-thiol is 440119-35-7.
What is the molecular formula of 4-(4-Chloro-phenyl)-1-(4-fluoro-phenyl)-1H-imidazole-2-thiol?
The molecular formula of 4-(4-Chloro-phenyl)-1-(4-fluoro-phenyl)-1H-imidazole-2-thiol is C15H10ClFN2S.
What is the molecular weight of 4-(4-Chloro-phenyl)-1-(4-fluoro-phenyl)-1H-imidazole-2-thiol?
The molecular weight of 4-(4-Chloro-phenyl)-1-(4-fluoro-phenyl)-1H-imidazole-2-thiol is 304.02 g/mol.
Where can I buy 4-(4-Chloro-phenyl)-1-(4-fluoro-phenyl)-1H-imidazole-2-thiol?
You can request a quote for 4-(4-Chloro-phenyl)-1-(4-fluoro-phenyl)-1H-imidazole-2-thiol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(4-Chloro-phenyl)-1-(4-fluoro-phenyl)-1H-imidazole-2-thiol?
Yes, KEHONG BIO provides custom synthesis services for 4-(4-Chloro-phenyl)-1-(4-fluoro-phenyl)-1H-imidazole-2-thiol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.