![1-{[2-(4-phenylpiperazino)-1,3-thiazol-5-yl]methyl}-1H-indole structure](/static/products/4390/439097-15-1.webp)
1-{[2-(4-phenylpiperazino)-1,3-thiazol-5-yl]methyl}-1H-indole
TL;DR: 1-{[2-(4-phenylpiperazino)-1,3-thiazol-5-yl]methyl}-1H-indole (CAS 439097-15-1) is a chemical compound with molecular formula C22H22N4S and molecular weight 374.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-(indol-1-ylmethyl)-2-(4-phenylpiperazin-1-yl)-1,3-thiazole
Also Known As: Bionet1_000028, MixCom2_000095, 1-{[2-(4-phenylpiperazino)-1,3-thiazol-5-yl]methyl}-1H-indole, 5-(indol-1-ylmethyl)-2-(4-phenylpiperazin-1-yl)-1,3-thiazole, 10R-0664
| Molecular Formula | C22H22N4S |
|---|---|
| Molecular Weight | 374.16 g/mol |
| LogP | 4.4727 |
| Topological Polar Surface Area | 24.3 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 374.15652 |
| Heavy Atoms | 27 |
| Complexity | 1028.6061 |
Chemical Identifiers
| CAS Number | 439097-15-1 |
|---|---|
| SMILES | C1CN(CCN1C2=CC=CC=C2)C3=NC=C(S3)CN4C=CC5=CC=CC=C54 |
Product Overview
1-{[2-(4-phenylpiperazino)-1,3-thiazol-5-yl]methyl}-1H-indole (CAS 439097-15-1), with molecular formula C22H22N4S and molecular weight 374.16 g/mol. IUPAC: 5-(indol-1-ylmethyl)-2-(4-phenylpiperazin-1-yl)-1,3-thiazole.
Chemical Property Profile of 1-{[2-(4-phenylpiperazino)-1,3-thiazol-5-yl]methyl}-1H-indole
Property Insights of 1-{[2-(4-phenylpiperazino)-1,3-thiazol-5-yl]methyl}-1H-indole
The XLogP value of 4.4727 indicates that 1-{[2-(4-phenylpiperazino)-1,3-thiazol-5-yl]methyl}-1H-indole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 24.3 Ų, 1-{[2-(4-phenylpiperazino)-1,3-thiazol-5-yl]methyl}-1H-indole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-{[2-(4-phenylpiperazino)-1,3-thiazol-5-yl]methyl}-1H-indole has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-{[2-(4-phenylpiperazino)-1,3-thiazol-5-yl]methyl}-1H-indole?
The CAS number of 1-{[2-(4-phenylpiperazino)-1,3-thiazol-5-yl]methyl}-1H-indole is 439097-15-1.
What is the molecular formula of 1-{[2-(4-phenylpiperazino)-1,3-thiazol-5-yl]methyl}-1H-indole?
The molecular formula of 1-{[2-(4-phenylpiperazino)-1,3-thiazol-5-yl]methyl}-1H-indole is C22H22N4S.
What is the molecular weight of 1-{[2-(4-phenylpiperazino)-1,3-thiazol-5-yl]methyl}-1H-indole?
The molecular weight of 1-{[2-(4-phenylpiperazino)-1,3-thiazol-5-yl]methyl}-1H-indole is 374.16 g/mol.
Where can I buy 1-{[2-(4-phenylpiperazino)-1,3-thiazol-5-yl]methyl}-1H-indole?
You can request a quote for 1-{[2-(4-phenylpiperazino)-1,3-thiazol-5-yl]methyl}-1H-indole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-{[2-(4-phenylpiperazino)-1,3-thiazol-5-yl]methyl}-1H-indole?
Yes, KEHONG BIO provides custom synthesis services for 1-{[2-(4-phenylpiperazino)-1,3-thiazol-5-yl]methyl}-1H-indole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.