10R-0051
TL;DR: 10R-0051 (CAS 439095-87-1) is a chemical compound with molecular formula C22H18FN5S and molecular weight 403.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[3-(2,5-dimethylpyrrol-1-yl)thiophen-2-yl]-6-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidin-7-amine
Also Known As: 10R-0051, 2-[3-(2,5-dimethylpyrrol-1-yl)thiophen-2-yl]-6-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidin-7-amine, 2-[3-(2,5-dimethyl-1H-pyrrol-1-yl)-2-thienyl]-6-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidin-7-amine, 2-[3-(2,5-dimethyl-1H-pyrrol-1-yl)thiophen-2-yl]-6-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidin-7-amine
| Molecular Formula | C22H18FN5S |
|---|---|
| Molecular Weight | 403.13 g/mol |
| LogP | 5.25364 |
| Topological Polar Surface Area | 61.14 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 403.1267 |
| Heavy Atoms | 29 |
| Complexity | 1324.316 |
Chemical Identifiers
| CAS Number | 439095-87-1 |
|---|---|
| SMILES | CC1=CC=C(N1C2=C(SC=C2)C3=NN4C(=C3)N=CC(=C4N)C5=CC=C(C=C5)F)C |
Product Overview
10R-0051 (CAS 439095-87-1), with molecular formula C22H18FN5S and molecular weight 403.13 g/mol. IUPAC: 2-[3-(2,5-dimethylpyrrol-1-yl)thiophen-2-yl]-6-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidin-7-amine.
Chemical Property Profile of 10R-0051
Property Insights of 10R-0051
The XLogP value of 5.25364 indicates that 10R-0051 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 61.14 Ų falls within the moderate polarity range, balancing permeability and solubility for 10R-0051. Following Lipinski's Rule of Five, 10R-0051 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 10R-0051?
The CAS number of 10R-0051 is 439095-87-1.
What is the molecular formula of 10R-0051?
The molecular formula of 10R-0051 is C22H18FN5S.
What is the molecular weight of 10R-0051?
The molecular weight of 10R-0051 is 403.13 g/mol.
Where can I buy 10R-0051?
You can request a quote for 10R-0051 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 10R-0051?
Yes, KEHONG BIO provides custom synthesis services for 10R-0051 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.