AF-399/41178823 structure

AF-399/41178823

TL;DR: AF-399/41178823 (CAS 438481-44-8) is a chemical compound with molecular formula C26H26N2O5 and molecular weight 446.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

N-[2-(3,4-dimethoxyphenyl)ethyl]-4-(1,3-dioxobenzo[de]isoquinolin-2-yl)butanamide

Also Known As: AF-399/41178823, N-[2-(3,4-dimethoxyphenyl)ethyl]-4-(1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)butanamide, F1161-0047, N-(3,4-dimethoxyphenethyl)-4-(1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)butanamide, N-[2-(3,4-dimethoxyphenyl)ethyl]-4-(1,3-dioxobenzo[de]isoquinolin-2-yl)butanamide

CAS: 438481-44-8
Molecular Formula C26H26N2O5
Molecular Weight 446.18 g/mol
LogP 3.5921
Topological Polar Surface Area 84.94 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 5
Rotatable Bonds 9
Exact Mass 446.18417
Heavy Atoms 33
Complexity 1169.7778

Chemical Identifiers

CAS Number 438481-44-8
SMILES COC1=C(C=C(C=C1)CCNC(=O)CCCN2C(=O)C3=CC=CC4=C3C(=CC=C4)C2=O)OC

Product Overview

AF-399/41178823 (CAS 438481-44-8), with molecular formula C26H26N2O5 and molecular weight 446.18 g/mol. IUPAC: N-[2-(3,4-dimethoxyphenyl)ethyl]-4-(1,3-dioxobenzo[de]isoquinolin-2-yl)butanamide.

🧪
Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of AF-399/41178823

XLogP
3.5921
TPSA (Topological Polar Surface Area)
84.94
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
5
Rotatable Bonds
9
Heavy Atoms
33
Complexity
1169.7778
Exact Mass
446.18417
Monoisotopic Mass
446.18417
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of AF-399/41178823

The XLogP value of 3.5921 indicates that AF-399/41178823 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 84.94 Ų falls within the moderate polarity range, balancing permeability and solubility for AF-399/41178823. Following Lipinski's Rule of Five, AF-399/41178823 has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of AF-399/41178823?

The CAS number of AF-399/41178823 is 438481-44-8.

What is the molecular formula of AF-399/41178823?

The molecular formula of AF-399/41178823 is C26H26N2O5.

What is the molecular weight of AF-399/41178823?

The molecular weight of AF-399/41178823 is 446.18 g/mol.

Where can I buy AF-399/41178823?

You can request a quote for AF-399/41178823 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for AF-399/41178823?

Yes, KEHONG BIO provides custom synthesis services for AF-399/41178823 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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