2-(5-chloro-2-thienyl)-N-(2,4-dimethoxyphenyl)-4-quinolinecarboxamide structure

2-(5-chloro-2-thienyl)-N-(2,4-dimethoxyphenyl)-4-quinolinecarboxamide

TL;DR: 2-(5-chloro-2-thienyl)-N-(2,4-dimethoxyphenyl)-4-quinolinecarboxamide (CAS 438474-65-8) is a chemical compound with molecular formula C22H17ClN2O3S and molecular weight 424.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-(5-chlorothiophen-2-yl)-N-(2,4-dimethoxyphenyl)quinoline-4-carboxamide

Also Known As: 2-(5-chloro-2-thienyl)-N-(2,4-dimethoxyphenyl)-4-quinolinecarboxamide, 2-(5-chlorothiophen-2-yl)-N-(2,4-dimethoxyphenyl)quinoline-4-carboxamide

CAS: 438474-65-8
Molecular Formula C22H17ClN2O3S
Molecular Weight 424.06 g/mol
LogP 5.8862
Topological Polar Surface Area 60.45 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 5
Rotatable Bonds 5
Exact Mass 424.06485
Heavy Atoms 29
Complexity 1205.8645

Chemical Identifiers

CAS Number 438474-65-8
SMILES COC1=CC(=C(C=C1)NC(=O)C2=CC(=NC3=CC=CC=C32)C4=CC=C(S4)Cl)OC

Product Overview

2-(5-chloro-2-thienyl)-N-(2,4-dimethoxyphenyl)-4-quinolinecarboxamide (CAS 438474-65-8), with molecular formula C22H17ClN2O3S and molecular weight 424.06 g/mol. IUPAC: 2-(5-chlorothiophen-2-yl)-N-(2,4-dimethoxyphenyl)quinoline-4-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 2-(5-chloro-2-thienyl)-N-(2,4-dimethoxyphenyl)-4-quinolinecarboxamide

XLogP
5.8862
TPSA (Topological Polar Surface Area)
60.45
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
5
Rotatable Bonds
5
Heavy Atoms
29
Complexity
1205.8645
Exact Mass
424.06485
Monoisotopic Mass
424.06485
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 2-(5-chloro-2-thienyl)-N-(2,4-dimethoxyphenyl)-4-quinolinecarboxamide

The XLogP value of 5.8862 indicates that 2-(5-chloro-2-thienyl)-N-(2,4-dimethoxyphenyl)-4-quinolinecarboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 60.45 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-(5-chloro-2-thienyl)-N-(2,4-dimethoxyphenyl)-4-quinolinecarboxamide. Following Lipinski's Rule of Five, 2-(5-chloro-2-thienyl)-N-(2,4-dimethoxyphenyl)-4-quinolinecarboxamide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 2-(5-chloro-2-thienyl)-N-(2,4-dimethoxyphenyl)-4-quinolinecarboxamide?

The CAS number of 2-(5-chloro-2-thienyl)-N-(2,4-dimethoxyphenyl)-4-quinolinecarboxamide is 438474-65-8.

What is the molecular formula of 2-(5-chloro-2-thienyl)-N-(2,4-dimethoxyphenyl)-4-quinolinecarboxamide?

The molecular formula of 2-(5-chloro-2-thienyl)-N-(2,4-dimethoxyphenyl)-4-quinolinecarboxamide is C22H17ClN2O3S.

What is the molecular weight of 2-(5-chloro-2-thienyl)-N-(2,4-dimethoxyphenyl)-4-quinolinecarboxamide?

The molecular weight of 2-(5-chloro-2-thienyl)-N-(2,4-dimethoxyphenyl)-4-quinolinecarboxamide is 424.06 g/mol.

Where can I buy 2-(5-chloro-2-thienyl)-N-(2,4-dimethoxyphenyl)-4-quinolinecarboxamide?

You can request a quote for 2-(5-chloro-2-thienyl)-N-(2,4-dimethoxyphenyl)-4-quinolinecarboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 2-(5-chloro-2-thienyl)-N-(2,4-dimethoxyphenyl)-4-quinolinecarboxamide?

Yes, KEHONG BIO provides custom synthesis services for 2-(5-chloro-2-thienyl)-N-(2,4-dimethoxyphenyl)-4-quinolinecarboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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