![[5-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(2-hydroxyphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone structure](/static/products/4382/438236-58-9.webp)
[5-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(2-hydroxyphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone
TL;DR: [5-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(2-hydroxyphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone (CAS 438236-58-9) is a chemical compound with molecular formula C34H28F3N5O4 and molecular weight 627.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[5-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(2-hydroxyphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone
Also Known As: [5-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(2-hydroxyphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone, 2-(3-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-{[5-(4-isopropylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]carbonyl}-4,5-dihydro-1H-pyrazol-5-yl)phenol, [3-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-5-(2-HYDROXYPHENYL)-4,5-DIHYDRO-1H-PYRAZOL-1-YL][5-(4-ISOPROPYLPHENYL)-7-(TRIFLUOROMETHYL)PYRAZOLO[1,5-A]PYRIMIDIN-2-YL]METHANONE, [3-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(2-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]{5-[4-(propan-2-yl)phenyl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl}methanone
| Molecular Formula | C34H28F3N5O4 |
|---|---|
| Molecular Weight | 627.21 g/mol |
| LogP | 7.0068 |
| Topological Polar Surface Area | 101.55 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 5 |
| Exact Mass | 627.20935 |
| Heavy Atoms | 46 |
| Complexity | 2002.9379 |
Chemical Identifiers
| CAS Number | 438236-58-9 |
|---|---|
| SMILES | CC(C)C1=CC=C(C=C1)C2=NC3=CC(=NN3C(=C2)C(F)(F)F)C(=O)N4C(CC(=N4)C5=CC6=C(C=C5)OCCO6)C7=CC=CC=C7O |
Product Overview
[5-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(2-hydroxyphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone (CAS 438236-58-9), with molecular formula C34H28F3N5O4 and molecular weight 627.21 g/mol. IUPAC: [5-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(2-hydroxyphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone.
Chemical Property Profile of [5-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(2-hydroxyphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone
Property Insights of [5-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(2-hydroxyphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone
The XLogP value of 7.0068 indicates that [5-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(2-hydroxyphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 101.55 Ų falls within the moderate polarity range, balancing permeability and solubility for [5-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(2-hydroxyphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone. Following Lipinski's Rule of Five, [5-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(2-hydroxyphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of [5-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(2-hydroxyphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone?
The CAS number of [5-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(2-hydroxyphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone is 438236-58-9.
What is the molecular formula of [5-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(2-hydroxyphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone?
The molecular formula of [5-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(2-hydroxyphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone is C34H28F3N5O4.
What is the molecular weight of [5-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(2-hydroxyphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone?
The molecular weight of [5-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(2-hydroxyphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone is 627.21 g/mol.
Where can I buy [5-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(2-hydroxyphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone?
You can request a quote for [5-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(2-hydroxyphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for [5-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(2-hydroxyphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone?
Yes, KEHONG BIO provides custom synthesis services for [5-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(2-hydroxyphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.