![[4-(3-chlorophenyl)piperazin-1-yl]-[5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone structure](/static/products/4382/438235-43-9.webp)
[4-(3-chlorophenyl)piperazin-1-yl]-[5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone
TL;DR: [4-(3-chlorophenyl)piperazin-1-yl]-[5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone (CAS 438235-43-9) is a chemical compound with molecular formula C22H16Cl2F3N5OS and molecular weight 525.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[4-(3-chlorophenyl)piperazin-1-yl]-[5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone
Also Known As: [4-(3-chlorophenyl)piperazin-1-yl]-[5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone, 2-{[4-(3-chlorophenyl)-1-piperazinyl]carbonyl}-5-(5-chloro-2-thienyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine, [4-(3-chlorophenyl)piperazin-1-yl][5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone, 5-(5-chloro(2-thienyl))-7-(trifluoromethyl)(8-hydropyrazolo[1,5-a]pyrimidin-2- yl) 4-(3-chlorophenyl)piperazinyl ketone
| Molecular Formula | C22H16Cl2F3N5OS |
|---|---|
| Molecular Weight | 525.04 g/mol |
| LogP | 5.7458 |
| Topological Polar Surface Area | 53.74 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 525.04047 |
| Heavy Atoms | 34 |
| Complexity | 1378.6277 |
Chemical Identifiers
| CAS Number | 438235-43-9 |
|---|---|
| SMILES | C1CN(CCN1C2=CC(=CC=C2)Cl)C(=O)C3=NN4C(=CC(=NC4=C3)C5=CC=C(S5)Cl)C(F)(F)F |
Product Overview
[4-(3-chlorophenyl)piperazin-1-yl]-[5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone (CAS 438235-43-9), with molecular formula C22H16Cl2F3N5OS and molecular weight 525.04 g/mol. IUPAC: [4-(3-chlorophenyl)piperazin-1-yl]-[5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone.
Chemical Property Profile of [4-(3-chlorophenyl)piperazin-1-yl]-[5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone
Property Insights of [4-(3-chlorophenyl)piperazin-1-yl]-[5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone
The XLogP value of 5.7458 indicates that [4-(3-chlorophenyl)piperazin-1-yl]-[5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 53.74 Ų, [4-(3-chlorophenyl)piperazin-1-yl]-[5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, [4-(3-chlorophenyl)piperazin-1-yl]-[5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of [4-(3-chlorophenyl)piperazin-1-yl]-[5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone?
The CAS number of [4-(3-chlorophenyl)piperazin-1-yl]-[5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone is 438235-43-9.
What is the molecular formula of [4-(3-chlorophenyl)piperazin-1-yl]-[5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone?
The molecular formula of [4-(3-chlorophenyl)piperazin-1-yl]-[5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone is C22H16Cl2F3N5OS.
What is the molecular weight of [4-(3-chlorophenyl)piperazin-1-yl]-[5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone?
The molecular weight of [4-(3-chlorophenyl)piperazin-1-yl]-[5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone is 525.04 g/mol.
Where can I buy [4-(3-chlorophenyl)piperazin-1-yl]-[5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone?
You can request a quote for [4-(3-chlorophenyl)piperazin-1-yl]-[5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for [4-(3-chlorophenyl)piperazin-1-yl]-[5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone?
Yes, KEHONG BIO provides custom synthesis services for [4-(3-chlorophenyl)piperazin-1-yl]-[5-(5-chlorothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.