![N-(3-cyano-4-ethyl-5-methylthiophen-2-yl)-5-(5-ethylthiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide structure](/static/products/4382/438234-57-2.webp)
N-(3-cyano-4-ethyl-5-methylthiophen-2-yl)-5-(5-ethylthiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
TL;DR: N-(3-cyano-4-ethyl-5-methylthiophen-2-yl)-5-(5-ethylthiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide (CAS 438234-57-2) is a chemical compound with molecular formula C22H18F3N5OS2 and molecular weight 489.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(3-cyano-4-ethyl-5-methylthiophen-2-yl)-5-(5-ethylthiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
Also Known As: N-(3-cyano-4-ethyl-5-methylthiophen-2-yl)-5-(5-ethylthiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide, N-(3-cyano-4-ethyl-5-methyl(2-thienyl))[5-(5-ethyl(2-thienyl))-7-(trifluoromet hyl)(8-hydropyrazolo[1,5-a]pyrimidin-2-yl)]carboxamide, N-(3-cyano-4-ethyl-5-methyl-2-thienyl)-5-(5-ethyl-2-thienyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
| Molecular Formula | C22H18F3N5OS2 |
|---|---|
| Molecular Weight | 489.09 g/mol |
| LogP | 6.0953 |
| Topological Polar Surface Area | 83.08 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 489.09048 |
| Heavy Atoms | 33 |
| Complexity | 1408.0155 |
Chemical Identifiers
| CAS Number | 438234-57-2 |
|---|---|
| SMILES | CCC1=CC=C(S1)C2=NC3=CC(=NN3C(=C2)C(F)(F)F)C(=O)NC4=C(C(=C(S4)C)CC)C#N |
Product Overview
N-(3-cyano-4-ethyl-5-methylthiophen-2-yl)-5-(5-ethylthiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide (CAS 438234-57-2), with molecular formula C22H18F3N5OS2 and molecular weight 489.09 g/mol. IUPAC: N-(3-cyano-4-ethyl-5-methylthiophen-2-yl)-5-(5-ethylthiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide.
Chemical Property Profile of N-(3-cyano-4-ethyl-5-methylthiophen-2-yl)-5-(5-ethylthiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
Property Insights of N-(3-cyano-4-ethyl-5-methylthiophen-2-yl)-5-(5-ethylthiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
The XLogP value of 6.0953 indicates that N-(3-cyano-4-ethyl-5-methylthiophen-2-yl)-5-(5-ethylthiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 83.08 Ų falls within the moderate polarity range, balancing permeability and solubility for N-(3-cyano-4-ethyl-5-methylthiophen-2-yl)-5-(5-ethylthiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide. Following Lipinski's Rule of Five, N-(3-cyano-4-ethyl-5-methylthiophen-2-yl)-5-(5-ethylthiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(3-cyano-4-ethyl-5-methylthiophen-2-yl)-5-(5-ethylthiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide?
The CAS number of N-(3-cyano-4-ethyl-5-methylthiophen-2-yl)-5-(5-ethylthiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide is 438234-57-2.
What is the molecular formula of N-(3-cyano-4-ethyl-5-methylthiophen-2-yl)-5-(5-ethylthiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide?
The molecular formula of N-(3-cyano-4-ethyl-5-methylthiophen-2-yl)-5-(5-ethylthiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide is C22H18F3N5OS2.
What is the molecular weight of N-(3-cyano-4-ethyl-5-methylthiophen-2-yl)-5-(5-ethylthiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide?
The molecular weight of N-(3-cyano-4-ethyl-5-methylthiophen-2-yl)-5-(5-ethylthiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide is 489.09 g/mol.
Where can I buy N-(3-cyano-4-ethyl-5-methylthiophen-2-yl)-5-(5-ethylthiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide?
You can request a quote for N-(3-cyano-4-ethyl-5-methylthiophen-2-yl)-5-(5-ethylthiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(3-cyano-4-ethyl-5-methylthiophen-2-yl)-5-(5-ethylthiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for N-(3-cyano-4-ethyl-5-methylthiophen-2-yl)-5-(5-ethylthiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.