![3,5-bis(difluoromethyl)-1-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}-4,5-dihydro-1H-pyrazol-5-ol structure](/static/products/4382/438234-08-3.webp)
3,5-bis(difluoromethyl)-1-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}-4,5-dihydro-1H-pyrazol-5-ol
TL;DR: 3,5-bis(difluoromethyl)-1-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}-4,5-dihydro-1H-pyrazol-5-ol (CAS 438234-08-3) is a chemical compound with molecular formula C16H14F8N2O3 and molecular weight 434.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-[3-(2,2,3,3-tetrafluoropropoxymethyl)phenyl]methanone
Also Known As: 3,5-bis(difluoromethyl)-1-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}-4,5-dihydro-1H-pyrazol-5-ol, [3,5-bis(difluoromethyl)-5-hydroxy-4,5-dihydro-1H-pyrazol-1-yl]{3-[(2,2,3,3-tetrafluoropropoxy)methyl]phenyl}methanone, [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-[3-(2,2,3,3-tetrafluoropropoxymethyl)phenyl]methanone
| Molecular Formula | C16H14F8N2O3 |
|---|---|
| Molecular Weight | 434.09 g/mol |
| LogP | 3.5243 |
| Topological Polar Surface Area | 62.13 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 8 |
| Exact Mass | 434.08768 |
| Heavy Atoms | 29 |
| Complexity | 774.2867 |
Chemical Identifiers
| CAS Number | 438234-08-3 |
|---|---|
| SMILES | C1C(=NN(C1(C(F)F)O)C(=O)C2=CC=CC(=C2)COCC(C(F)F)(F)F)C(F)F |
Product Overview
3,5-bis(difluoromethyl)-1-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}-4,5-dihydro-1H-pyrazol-5-ol (CAS 438234-08-3), with molecular formula C16H14F8N2O3 and molecular weight 434.09 g/mol. IUPAC: [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-[3-(2,2,3,3-tetrafluoropropoxymethyl)phenyl]methanone.
Chemical Property Profile of 3,5-bis(difluoromethyl)-1-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}-4,5-dihydro-1H-pyrazol-5-ol
Property Insights of 3,5-bis(difluoromethyl)-1-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}-4,5-dihydro-1H-pyrazol-5-ol
The XLogP value of 3.5243 indicates that 3,5-bis(difluoromethyl)-1-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}-4,5-dihydro-1H-pyrazol-5-ol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 62.13 Ų falls within the moderate polarity range, balancing permeability and solubility for 3,5-bis(difluoromethyl)-1-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}-4,5-dihydro-1H-pyrazol-5-ol. Following Lipinski's Rule of Five, 3,5-bis(difluoromethyl)-1-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}-4,5-dihydro-1H-pyrazol-5-ol has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3,5-bis(difluoromethyl)-1-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}-4,5-dihydro-1H-pyrazol-5-ol?
The CAS number of 3,5-bis(difluoromethyl)-1-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}-4,5-dihydro-1H-pyrazol-5-ol is 438234-08-3.
What is the molecular formula of 3,5-bis(difluoromethyl)-1-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}-4,5-dihydro-1H-pyrazol-5-ol?
The molecular formula of 3,5-bis(difluoromethyl)-1-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}-4,5-dihydro-1H-pyrazol-5-ol is C16H14F8N2O3.
What is the molecular weight of 3,5-bis(difluoromethyl)-1-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}-4,5-dihydro-1H-pyrazol-5-ol?
The molecular weight of 3,5-bis(difluoromethyl)-1-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}-4,5-dihydro-1H-pyrazol-5-ol is 434.09 g/mol.
Where can I buy 3,5-bis(difluoromethyl)-1-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}-4,5-dihydro-1H-pyrazol-5-ol?
You can request a quote for 3,5-bis(difluoromethyl)-1-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}-4,5-dihydro-1H-pyrazol-5-ol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3,5-bis(difluoromethyl)-1-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}-4,5-dihydro-1H-pyrazol-5-ol?
Yes, KEHONG BIO provides custom synthesis services for 3,5-bis(difluoromethyl)-1-{3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoyl}-4,5-dihydro-1H-pyrazol-5-ol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.