![[3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-[2-(2,4-dimethylphenyl)quinolin-4-yl]methanone structure](/static/products/4382/438231-55-1.webp)
[3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-[2-(2,4-dimethylphenyl)quinolin-4-yl]methanone
TL;DR: [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-[2-(2,4-dimethylphenyl)quinolin-4-yl]methanone (CAS 438231-55-1) is a chemical compound with molecular formula C23H19F4N3O2 and molecular weight 445.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-[2-(2,4-dimethylphenyl)quinolin-4-yl]methanone
Also Known As: [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-[2-(2,4-dimethylphenyl)quinolin-4-yl]methanone, [3,5-bis(difluoromethyl)-5-hydroxy-4,5-dihydro-1H-pyrazol-1-yl][2-(2,4-dimethylphenyl)quinolin-4-yl]methanone, [3,5-BIS(DIFLUOROMETHYL)-5-HYDROXY-4,5-DIHYDRO-1H-PYRAZOL-1-YL][2-(2,4-DIMETHYLPHENYL)-4-QUINOLYL]METHANONE, 3,5-bis(difluoromethyl)-1-{[2-(2,4-dimethylphenyl)-4-quinolinyl]carbonyl}-4,5-dihydro-1H-pyrazol-5-ol, 3,5-bis(difluoromethyl)-5-hydroxy(2-pyrazolinyl) 2-(2,4-dimethylphenyl)(4-quin olyl) ketone
| Molecular Formula | C23H19F4N3O2 |
|---|---|
| Molecular Weight | 445.14 g/mol |
| LogP | 4.93934 |
| Topological Polar Surface Area | 65.79 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 445.14133 |
| Heavy Atoms | 32 |
| Complexity | 1245.1387 |
Chemical Identifiers
| CAS Number | 438231-55-1 |
|---|---|
| SMILES | CC1=CC(=C(C=C1)C2=NC3=CC=CC=C3C(=C2)C(=O)N4C(CC(=N4)C(F)F)(C(F)F)O)C |
Product Overview
[3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-[2-(2,4-dimethylphenyl)quinolin-4-yl]methanone (CAS 438231-55-1), with molecular formula C23H19F4N3O2 and molecular weight 445.14 g/mol. IUPAC: [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-[2-(2,4-dimethylphenyl)quinolin-4-yl]methanone.
Chemical Property Profile of [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-[2-(2,4-dimethylphenyl)quinolin-4-yl]methanone
Property Insights of [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-[2-(2,4-dimethylphenyl)quinolin-4-yl]methanone
The XLogP value of 4.93934 indicates that [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-[2-(2,4-dimethylphenyl)quinolin-4-yl]methanone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 65.79 Ų falls within the moderate polarity range, balancing permeability and solubility for [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-[2-(2,4-dimethylphenyl)quinolin-4-yl]methanone. Following Lipinski's Rule of Five, [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-[2-(2,4-dimethylphenyl)quinolin-4-yl]methanone has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-[2-(2,4-dimethylphenyl)quinolin-4-yl]methanone?
The CAS number of [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-[2-(2,4-dimethylphenyl)quinolin-4-yl]methanone is 438231-55-1.
What is the molecular formula of [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-[2-(2,4-dimethylphenyl)quinolin-4-yl]methanone?
The molecular formula of [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-[2-(2,4-dimethylphenyl)quinolin-4-yl]methanone is C23H19F4N3O2.
What is the molecular weight of [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-[2-(2,4-dimethylphenyl)quinolin-4-yl]methanone?
The molecular weight of [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-[2-(2,4-dimethylphenyl)quinolin-4-yl]methanone is 445.14 g/mol.
Where can I buy [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-[2-(2,4-dimethylphenyl)quinolin-4-yl]methanone?
You can request a quote for [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-[2-(2,4-dimethylphenyl)quinolin-4-yl]methanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-[2-(2,4-dimethylphenyl)quinolin-4-yl]methanone?
Yes, KEHONG BIO provides custom synthesis services for [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-[2-(2,4-dimethylphenyl)quinolin-4-yl]methanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.