![[3-(2-hydroxyphenyl)-5-(4-phenylphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone structure](/static/products/4382/438231-32-4.webp)
[3-(2-hydroxyphenyl)-5-(4-phenylphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone
TL;DR: [3-(2-hydroxyphenyl)-5-(4-phenylphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone (CAS 438231-32-4) is a chemical compound with molecular formula C38H30F3N5O2 and molecular weight 645.24 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[3-(2-hydroxyphenyl)-5-(4-phenylphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone
Also Known As: [3-(2-hydroxyphenyl)-5-(4-phenylphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone, [3-(biphenyl-4-yl)-5-(2-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]{5-[4-(propan-2-yl)phenyl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl}methanone, 2-(3-[1,1'-biphenyl]-4-yl-1-{[5-(4-isopropylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]carbonyl}-4,5-dihydro-1H-pyrazol-5-yl)phenol
| Molecular Formula | C38H30F3N5O2 |
|---|---|
| Molecular Weight | 645.24 g/mol |
| LogP | 8.9026 |
| Topological Polar Surface Area | 83.09 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 645.23517 |
| Heavy Atoms | 48 |
| Complexity | 2156.1748 |
Chemical Identifiers
| CAS Number | 438231-32-4 |
|---|---|
| SMILES | CC(C)C1=CC=C(C=C1)C2=NC3=CC(=NN3C(=C2)C(F)(F)F)C(=O)N4C(CC(=N4)C5=CC=C(C=C5)C6=CC=CC=C6)C7=CC=CC=C7O |
Product Overview
[3-(2-hydroxyphenyl)-5-(4-phenylphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone (CAS 438231-32-4), with molecular formula C38H30F3N5O2 and molecular weight 645.24 g/mol. IUPAC: [3-(2-hydroxyphenyl)-5-(4-phenylphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone.
Chemical Property Profile of [3-(2-hydroxyphenyl)-5-(4-phenylphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone
Property Insights of [3-(2-hydroxyphenyl)-5-(4-phenylphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone
The XLogP value of 8.9026 indicates that [3-(2-hydroxyphenyl)-5-(4-phenylphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 83.09 Ų falls within the moderate polarity range, balancing permeability and solubility for [3-(2-hydroxyphenyl)-5-(4-phenylphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone. Following Lipinski's Rule of Five, [3-(2-hydroxyphenyl)-5-(4-phenylphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of [3-(2-hydroxyphenyl)-5-(4-phenylphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone?
The CAS number of [3-(2-hydroxyphenyl)-5-(4-phenylphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone is 438231-32-4.
What is the molecular formula of [3-(2-hydroxyphenyl)-5-(4-phenylphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone?
The molecular formula of [3-(2-hydroxyphenyl)-5-(4-phenylphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone is C38H30F3N5O2.
What is the molecular weight of [3-(2-hydroxyphenyl)-5-(4-phenylphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone?
The molecular weight of [3-(2-hydroxyphenyl)-5-(4-phenylphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone is 645.24 g/mol.
Where can I buy [3-(2-hydroxyphenyl)-5-(4-phenylphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone?
You can request a quote for [3-(2-hydroxyphenyl)-5-(4-phenylphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for [3-(2-hydroxyphenyl)-5-(4-phenylphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone?
Yes, KEHONG BIO provides custom synthesis services for [3-(2-hydroxyphenyl)-5-(4-phenylphenyl)-3,4-dihydropyrazol-2-yl]-[5-(4-propan-2-ylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.