![[3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-(4-fluorophenyl)methanone structure](/static/products/4382/438228-94-5.webp)
[3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-(4-fluorophenyl)methanone
TL;DR: [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-(4-fluorophenyl)methanone (CAS 438228-94-5) is a chemical compound with molecular formula C12H9F5N2O2 and molecular weight 308.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-(4-fluorophenyl)methanone
Also Known As: [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-(4-fluorophenyl)methanone, [3,5-bis(difluoromethyl)-5-hydroxy-4,5-dihydro-1H-pyrazol-1-yl](4-fluorophenyl)methanone, 3,5-bis(difluoromethyl)-1-(4-fluorobenzoyl)-4,5-dihydro-1H-pyrazol-5-ol, 3,5-bis(difluoromethyl)-5-hydroxy(2-pyrazolinyl) 4-fluorophenyl ketone
| Molecular Formula | C12H9F5N2O2 |
|---|---|
| Molecular Weight | 308.06 g/mol |
| LogP | 2.2464 |
| Topological Polar Surface Area | 52.9 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 308.0584 |
| Heavy Atoms | 21 |
| Complexity | 575.51544 |
Chemical Identifiers
| CAS Number | 438228-94-5 |
|---|---|
| SMILES | C1C(=NN(C1(C(F)F)O)C(=O)C2=CC=C(C=C2)F)C(F)F |
Product Overview
[3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-(4-fluorophenyl)methanone (CAS 438228-94-5), with molecular formula C12H9F5N2O2 and molecular weight 308.06 g/mol. IUPAC: [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-(4-fluorophenyl)methanone.
Chemical Property Profile of [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-(4-fluorophenyl)methanone
Property Insights of [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-(4-fluorophenyl)methanone
The XLogP value of 2.2464 suggests moderate lipophilicity, balancing water solubility and membrane permeability for [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-(4-fluorophenyl)methanone. With a topological polar surface area (TPSA) of 52.9 Ų, [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-(4-fluorophenyl)methanone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-(4-fluorophenyl)methanone has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-(4-fluorophenyl)methanone?
The CAS number of [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-(4-fluorophenyl)methanone is 438228-94-5.
What is the molecular formula of [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-(4-fluorophenyl)methanone?
The molecular formula of [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-(4-fluorophenyl)methanone is C12H9F5N2O2.
What is the molecular weight of [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-(4-fluorophenyl)methanone?
The molecular weight of [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-(4-fluorophenyl)methanone is 308.06 g/mol.
Where can I buy [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-(4-fluorophenyl)methanone?
You can request a quote for [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-(4-fluorophenyl)methanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-(4-fluorophenyl)methanone?
Yes, KEHONG BIO provides custom synthesis services for [3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-(4-fluorophenyl)methanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.