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5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid
TL;DR: 5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 438227-84-0) is a chemical compound with molecular formula C9H5F4N3O2 and molecular weight 263.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5,7-bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid
Also Known As: 5,7-bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid, 5,7-bis(difluoromethyl)-8-hydropyrazolo[1,5-a]pyrimidine-2-carboxylic acid, 5,7-BIS-DIFLUOROMETHYL-PYRAZOLO[1,5-A]PYRIMIDINE-2-CARBOXYLIC ACID, pyrazolo[1,5-a]pyrimidine-2-carboxylic acid, 5,7-bis(difluoromethyl)-, 5,7-bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylicacid
| Molecular Formula | C9H5F4N3O2 |
|---|---|
| Molecular Weight | 263.03 g/mol |
| LogP | 1.5 |
| Topological Polar Surface Area | 67.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 3 |
| Exact Mass | 263.0318 |
| Heavy Atoms | 18 |
| Complexity | 331.0 |
Chemical Identifiers
| CAS Number | 438227-84-0 |
|---|---|
| SMILES | C1=C(N2C(=CC(=N2)C(=O)O)N=C1C(F)F)C(F)F |
| InChIKey | FRAHNBWWMSAPGA-UHFFFAOYSA-N |
Product Overview
5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 438227-84-0), with molecular formula C9H5F4N3O2 and molecular weight 263.03 g/mol. IUPAC: 5,7-bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid.
Chemical Property Profile of 5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid
Property Insights of 5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid
The XLogP value of 1.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid. The TPSA of 67.5 Ų falls within the moderate polarity range, balancing permeability and solubility for 5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid. Following Lipinski's Rule of Five, 5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid?
The CAS number of 5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid is 438227-84-0.
What is the molecular formula of 5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid?
The molecular formula of 5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid is C9H5F4N3O2.
What is the molecular weight of 5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid?
The molecular weight of 5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid is 263.03 g/mol.
Where can I buy 5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid?
You can request a quote for 5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid?
Yes, KEHONG BIO provides custom synthesis services for 5,7-Bis(difluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.