![1-[3-cyclopropyl-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-2-naphthalen-2-ylethanone structure](/static/products/4382/438227-13-5.webp)
1-[3-cyclopropyl-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-2-naphthalen-2-ylethanone
TL;DR: 1-[3-cyclopropyl-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-2-naphthalen-2-ylethanone (CAS 438227-13-5) is a chemical compound with molecular formula C19H17F3N2O2 and molecular weight 362.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[3-cyclopropyl-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-2-naphthalen-2-ylethanone
Also Known As: 1-[3-cyclopropyl-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-2-naphthalen-2-ylethanone, 1-[3-cyclopropyl-5-hydroxy-5-(trifluoromethyl)(2-pyrazolinyl)]-2-(2-naphthyl)e than-1-one, 1-[3-cyclopropyl-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-2-naphthalen-2-yl-ethanone, 1-[3-cyclopropyl-5-hydroxy-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-1-yl]-2-(naphthalen-2-yl)ethanone
| Molecular Formula | C19H17F3N2O2 |
|---|---|
| Molecular Weight | 362.12 g/mol |
| LogP | 3.6315 |
| Topological Polar Surface Area | 52.9 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 362.1242 |
| Heavy Atoms | 26 |
| Complexity | 905.03754 |
Chemical Identifiers
| CAS Number | 438227-13-5 |
|---|---|
| SMILES | C1CC1C2=NN(C(C2)(C(F)(F)F)O)C(=O)CC3=CC4=CC=CC=C4C=C3 |
Product Overview
1-[3-cyclopropyl-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-2-naphthalen-2-ylethanone (CAS 438227-13-5), with molecular formula C19H17F3N2O2 and molecular weight 362.12 g/mol. IUPAC: 1-[3-cyclopropyl-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-2-naphthalen-2-ylethanone.
Chemical Property Profile of 1-[3-cyclopropyl-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-2-naphthalen-2-ylethanone
Property Insights of 1-[3-cyclopropyl-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-2-naphthalen-2-ylethanone
The XLogP value of 3.6315 indicates that 1-[3-cyclopropyl-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-2-naphthalen-2-ylethanone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 52.9 Ų, 1-[3-cyclopropyl-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-2-naphthalen-2-ylethanone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-[3-cyclopropyl-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-2-naphthalen-2-ylethanone has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-[3-cyclopropyl-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-2-naphthalen-2-ylethanone?
The CAS number of 1-[3-cyclopropyl-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-2-naphthalen-2-ylethanone is 438227-13-5.
What is the molecular formula of 1-[3-cyclopropyl-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-2-naphthalen-2-ylethanone?
The molecular formula of 1-[3-cyclopropyl-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-2-naphthalen-2-ylethanone is C19H17F3N2O2.
What is the molecular weight of 1-[3-cyclopropyl-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-2-naphthalen-2-ylethanone?
The molecular weight of 1-[3-cyclopropyl-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-2-naphthalen-2-ylethanone is 362.12 g/mol.
Where can I buy 1-[3-cyclopropyl-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-2-naphthalen-2-ylethanone?
You can request a quote for 1-[3-cyclopropyl-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-2-naphthalen-2-ylethanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-[3-cyclopropyl-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-2-naphthalen-2-ylethanone?
Yes, KEHONG BIO provides custom synthesis services for 1-[3-cyclopropyl-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-2-naphthalen-2-ylethanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.