![N-[2-chloro-5-(trifluoromethyl)phenyl]-9-(trifluoromethyl)-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazoline-2-carboxamide structure](/static/products/4382/438223-58-6.webp)
N-[2-chloro-5-(trifluoromethyl)phenyl]-9-(trifluoromethyl)-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazoline-2-carboxamide
TL;DR: N-[2-chloro-5-(trifluoromethyl)phenyl]-9-(trifluoromethyl)-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazoline-2-carboxamide (CAS 438223-58-6) is a chemical compound with molecular formula C19H13ClF6N4O and molecular weight 462.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[2-chloro-5-(trifluoromethyl)phenyl]-9-(trifluoromethyl)-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazoline-2-carboxamide
Also Known As: N-[2-chloro-5-(trifluoromethyl)phenyl]-9-(trifluoromethyl)-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazoline-2-carboxamide, N-[2-CHLORO-5-(TRIFLUOROMETHYL)PHENYL]-9-(TRIFLUOROMETHYL)-5H,6H,7H,8H-PYRAZOLO[3,2-B]QUINAZOLINE-2-CARBOXAMIDE
| Molecular Formula | C19H13ClF6N4O |
|---|---|
| Molecular Weight | 462.07 g/mol |
| LogP | 5.5514 |
| Topological Polar Surface Area | 59.29 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 462.0682 |
| Heavy Atoms | 31 |
| Complexity | 1184.8254 |
Chemical Identifiers
| CAS Number | 438223-58-6 |
|---|---|
| SMILES | C1CCC2=NC3=CC(=NN3C(=C2C1)C(F)(F)F)C(=O)NC4=C(C=CC(=C4)C(F)(F)F)Cl |
Product Overview
N-[2-chloro-5-(trifluoromethyl)phenyl]-9-(trifluoromethyl)-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazoline-2-carboxamide (CAS 438223-58-6), with molecular formula C19H13ClF6N4O and molecular weight 462.07 g/mol. IUPAC: N-[2-chloro-5-(trifluoromethyl)phenyl]-9-(trifluoromethyl)-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazoline-2-carboxamide.
Chemical Property Profile of N-[2-chloro-5-(trifluoromethyl)phenyl]-9-(trifluoromethyl)-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazoline-2-carboxamide
Property Insights of N-[2-chloro-5-(trifluoromethyl)phenyl]-9-(trifluoromethyl)-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazoline-2-carboxamide
The XLogP value of 5.5514 indicates that N-[2-chloro-5-(trifluoromethyl)phenyl]-9-(trifluoromethyl)-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazoline-2-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 59.29 Ų, N-[2-chloro-5-(trifluoromethyl)phenyl]-9-(trifluoromethyl)-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazoline-2-carboxamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-[2-chloro-5-(trifluoromethyl)phenyl]-9-(trifluoromethyl)-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazoline-2-carboxamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-[2-chloro-5-(trifluoromethyl)phenyl]-9-(trifluoromethyl)-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazoline-2-carboxamide?
The CAS number of N-[2-chloro-5-(trifluoromethyl)phenyl]-9-(trifluoromethyl)-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazoline-2-carboxamide is 438223-58-6.
What is the molecular formula of N-[2-chloro-5-(trifluoromethyl)phenyl]-9-(trifluoromethyl)-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazoline-2-carboxamide?
The molecular formula of N-[2-chloro-5-(trifluoromethyl)phenyl]-9-(trifluoromethyl)-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazoline-2-carboxamide is C19H13ClF6N4O.
What is the molecular weight of N-[2-chloro-5-(trifluoromethyl)phenyl]-9-(trifluoromethyl)-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazoline-2-carboxamide?
The molecular weight of N-[2-chloro-5-(trifluoromethyl)phenyl]-9-(trifluoromethyl)-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazoline-2-carboxamide is 462.07 g/mol.
Where can I buy N-[2-chloro-5-(trifluoromethyl)phenyl]-9-(trifluoromethyl)-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazoline-2-carboxamide?
You can request a quote for N-[2-chloro-5-(trifluoromethyl)phenyl]-9-(trifluoromethyl)-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazoline-2-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-[2-chloro-5-(trifluoromethyl)phenyl]-9-(trifluoromethyl)-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazoline-2-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for N-[2-chloro-5-(trifluoromethyl)phenyl]-9-(trifluoromethyl)-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazoline-2-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.