N-(3-chloro-4-fluorophenyl)-4-(difluoromethoxy)benzamide
TL;DR: N-(3-chloro-4-fluorophenyl)-4-(difluoromethoxy)benzamide (CAS 438222-98-1) is a chemical compound with molecular formula C14H9ClF3NO2 and molecular weight 315.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(3-chloro-4-fluorophenyl)-4-(difluoromethoxy)benzamide
Also Known As: N-(3-chloro-4-fluorophenyl)-4-(difluoromethoxy)benzamide
| Molecular Formula | C14H9ClF3NO2 |
|---|---|
| Molecular Weight | 315.03 g/mol |
| LogP | 4.3328 |
| Topological Polar Surface Area | 38.33 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 4 |
| Exact Mass | 315.0274 |
| Heavy Atoms | 21 |
| Complexity | 647.1674 |
Chemical Identifiers
| CAS Number | 438222-98-1 |
|---|---|
| SMILES | C1=CC(=CC=C1C(=O)NC2=CC(=C(C=C2)F)Cl)OC(F)F |
Product Overview
N-(3-chloro-4-fluorophenyl)-4-(difluoromethoxy)benzamide (CAS 438222-98-1), with molecular formula C14H9ClF3NO2 and molecular weight 315.03 g/mol. IUPAC: N-(3-chloro-4-fluorophenyl)-4-(difluoromethoxy)benzamide.
Chemical Property Profile of N-(3-chloro-4-fluorophenyl)-4-(difluoromethoxy)benzamide
Property Insights of N-(3-chloro-4-fluorophenyl)-4-(difluoromethoxy)benzamide
The XLogP value of 4.3328 indicates that N-(3-chloro-4-fluorophenyl)-4-(difluoromethoxy)benzamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 38.33 Ų, N-(3-chloro-4-fluorophenyl)-4-(difluoromethoxy)benzamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(3-chloro-4-fluorophenyl)-4-(difluoromethoxy)benzamide has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(3-chloro-4-fluorophenyl)-4-(difluoromethoxy)benzamide?
The CAS number of N-(3-chloro-4-fluorophenyl)-4-(difluoromethoxy)benzamide is 438222-98-1.
What is the molecular formula of N-(3-chloro-4-fluorophenyl)-4-(difluoromethoxy)benzamide?
The molecular formula of N-(3-chloro-4-fluorophenyl)-4-(difluoromethoxy)benzamide is C14H9ClF3NO2.
What is the molecular weight of N-(3-chloro-4-fluorophenyl)-4-(difluoromethoxy)benzamide?
The molecular weight of N-(3-chloro-4-fluorophenyl)-4-(difluoromethoxy)benzamide is 315.03 g/mol.
Where can I buy N-(3-chloro-4-fluorophenyl)-4-(difluoromethoxy)benzamide?
You can request a quote for N-(3-chloro-4-fluorophenyl)-4-(difluoromethoxy)benzamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(3-chloro-4-fluorophenyl)-4-(difluoromethoxy)benzamide?
Yes, KEHONG BIO provides custom synthesis services for N-(3-chloro-4-fluorophenyl)-4-(difluoromethoxy)benzamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.