![[5-(3,4-dimethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-[4-(2-ethoxyphenyl)piperazin-1-yl]methanone structure](/static/products/4382/438217-94-8.webp)
[5-(3,4-dimethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-[4-(2-ethoxyphenyl)piperazin-1-yl]methanone
TL;DR: [5-(3,4-dimethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-[4-(2-ethoxyphenyl)piperazin-1-yl]methanone (CAS 438217-94-8) is a chemical compound with molecular formula C28H28F3N5O2 and molecular weight 523.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[5-(3,4-dimethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-[4-(2-ethoxyphenyl)piperazin-1-yl]methanone
Also Known As: [5-(3,4-dimethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-[4-(2-ethoxyphenyl)piperazin-1-yl]methanone, 5-(3,4-dimethylphenyl)-2-{[4-(2-ethoxyphenyl)-1-piperazinyl]carbonyl}-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine, [5-(3,4-dimethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl][4-(2-ethoxyphenyl)piperazin-1-yl]methanone, 5-(3,4-dimethylphenyl)-7-(trifluoromethyl)(8-hydropyrazolo[1,5-a]pyrimidin-2-y l) 4-(2-ethoxyphenyl)piperazinyl ketone
| Molecular Formula | C28H28F3N5O2 |
|---|---|
| Molecular Weight | 523.22 g/mol |
| LogP | 5.39304 |
| Topological Polar Surface Area | 62.97 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 523.2195 |
| Heavy Atoms | 38 |
| Complexity | 1489.8684 |
Chemical Identifiers
| CAS Number | 438217-94-8 |
|---|---|
| SMILES | CCOC1=CC=CC=C1N2CCN(CC2)C(=O)C3=NN4C(=CC(=NC4=C3)C5=CC(=C(C=C5)C)C)C(F)(F)F |
Product Overview
[5-(3,4-dimethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-[4-(2-ethoxyphenyl)piperazin-1-yl]methanone (CAS 438217-94-8), with molecular formula C28H28F3N5O2 and molecular weight 523.22 g/mol. IUPAC: [5-(3,4-dimethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-[4-(2-ethoxyphenyl)piperazin-1-yl]methanone.
Chemical Property Profile of [5-(3,4-dimethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-[4-(2-ethoxyphenyl)piperazin-1-yl]methanone
Property Insights of [5-(3,4-dimethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-[4-(2-ethoxyphenyl)piperazin-1-yl]methanone
The XLogP value of 5.39304 indicates that [5-(3,4-dimethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-[4-(2-ethoxyphenyl)piperazin-1-yl]methanone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 62.97 Ų falls within the moderate polarity range, balancing permeability and solubility for [5-(3,4-dimethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-[4-(2-ethoxyphenyl)piperazin-1-yl]methanone. Following Lipinski's Rule of Five, [5-(3,4-dimethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-[4-(2-ethoxyphenyl)piperazin-1-yl]methanone has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of [5-(3,4-dimethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-[4-(2-ethoxyphenyl)piperazin-1-yl]methanone?
The CAS number of [5-(3,4-dimethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-[4-(2-ethoxyphenyl)piperazin-1-yl]methanone is 438217-94-8.
What is the molecular formula of [5-(3,4-dimethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-[4-(2-ethoxyphenyl)piperazin-1-yl]methanone?
The molecular formula of [5-(3,4-dimethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-[4-(2-ethoxyphenyl)piperazin-1-yl]methanone is C28H28F3N5O2.
What is the molecular weight of [5-(3,4-dimethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-[4-(2-ethoxyphenyl)piperazin-1-yl]methanone?
The molecular weight of [5-(3,4-dimethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-[4-(2-ethoxyphenyl)piperazin-1-yl]methanone is 523.22 g/mol.
Where can I buy [5-(3,4-dimethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-[4-(2-ethoxyphenyl)piperazin-1-yl]methanone?
You can request a quote for [5-(3,4-dimethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-[4-(2-ethoxyphenyl)piperazin-1-yl]methanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for [5-(3,4-dimethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-[4-(2-ethoxyphenyl)piperazin-1-yl]methanone?
Yes, KEHONG BIO provides custom synthesis services for [5-(3,4-dimethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-[4-(2-ethoxyphenyl)piperazin-1-yl]methanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.