(-)-Epipodophyllotoxin
TL;DR: (-)-Epipodophyllotoxin (CAS 4375-07-9) is a chemical compound with molecular formula C22H22O8 and molecular weight 414.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5S,5aR,8aR,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one
Also Known As: Epipodophyllotoxin, (-)-epipodophyllotoxin, Etopside, podophyllotoxin, epi-Podophyllotoxin
| Molecular Formula | C22H22O8 |
|---|---|
| Molecular Weight | 414.13 g/mol |
| LogP | 2.0 |
| Topological Polar Surface Area | 92.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 4 |
| Exact Mass | 414.13147 |
| Heavy Atoms | 30 |
| Complexity | 629.0 |
Chemical Identifiers
| CAS Number | 4375-07-9 |
|---|---|
| SMILES | COC1=CC(=CC(=C1OC)OC)[C@H]2[C@@H]3[C@H](COC3=O)[C@@H](C4=CC5=C(C=C24)OCO5)O |
| InChIKey | YJGVMLPVUAXIQN-LGWHJFRWSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
(-)-Epipodophyllotoxin (CAS 4375-07-9), with molecular formula C22H22O8 and molecular weight 414.13 g/mol. IUPAC: (5S,5aR,8aR,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one.
Chemical Property Profile of (-)-Epipodophyllotoxin
Property Insights of (-)-Epipodophyllotoxin
The XLogP value of 2.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (-)-Epipodophyllotoxin. The TPSA of 92.7 Ų falls within the moderate polarity range, balancing permeability and solubility for (-)-Epipodophyllotoxin. Following Lipinski's Rule of Five, (-)-Epipodophyllotoxin has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (-)-Epipodophyllotoxin?
The CAS number of (-)-Epipodophyllotoxin is 4375-07-9.
What is the molecular formula of (-)-Epipodophyllotoxin?
The molecular formula of (-)-Epipodophyllotoxin is C22H22O8.
What is the molecular weight of (-)-Epipodophyllotoxin?
The molecular weight of (-)-Epipodophyllotoxin is 414.13 g/mol.
Where can I buy (-)-Epipodophyllotoxin?
You can request a quote for (-)-Epipodophyllotoxin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (-)-Epipodophyllotoxin?
Yes, KEHONG BIO provides custom synthesis services for (-)-Epipodophyllotoxin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.