alpha-Hydrastine structure

alpha-Hydrastine

TL;DR: alpha-Hydrastine (CAS 4370-85-8) is a chemical compound with molecular formula C21H21NO6 and molecular weight 383.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

3-(9a-methyl-4,9-dihydro-3aH-[1,3]dioxolo[4,5-g]isoquinolin-9-yl)-6,7-dimethoxy-3H-2-benzofuran-1-one

Also Known As: alpha-Hydrastine, (-)-alpha-Hydrastine, (R-(R*,R*))-6,7-Dimethoxy-3-(5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-1(3H)-isobenzofuranone, 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-, (R-(R*,R*))-, 3-(9a-methyl-4,9-dihydro-3aH-[1,3]dioxolo[4,5-g]isoquinolin-9-yl)-6,7-dimethoxy-3H-2-benzofuran-1-one

CAS: 4370-85-8
Molecular Formula C21H21NO6
Molecular Weight 383.14 g/mol
LogP 2.7818
Topological Polar Surface Area 76.11 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 7
Rotatable Bonds 3
Exact Mass 383.1369
Heavy Atoms 28
Complexity 959.90717

Chemical Identifiers

CAS Number 4370-85-8
SMILES CC12C(CC3=C(C1C4C5=C(C(=C(C=C5)OC)OC)C(=O)O4)C=CN=C3)OCO2

Product Overview

alpha-Hydrastine (CAS 4370-85-8), with molecular formula C21H21NO6 and molecular weight 383.14 g/mol. IUPAC: 3-(9a-methyl-4,9-dihydro-3aH-[1,3]dioxolo[4,5-g]isoquinolin-9-yl)-6,7-dimethoxy-3H-2-benzofuran-1-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of alpha-Hydrastine

XLogP
2.7818
TPSA (Topological Polar Surface Area)
76.11
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
7
Rotatable Bonds
3
Heavy Atoms
28
Complexity
959.90717
Exact Mass
383.1369
Monoisotopic Mass
383.1369
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of alpha-Hydrastine

The XLogP value of 2.7818 suggests moderate lipophilicity, balancing water solubility and membrane permeability for alpha-Hydrastine. The TPSA of 76.11 Ų falls within the moderate polarity range, balancing permeability and solubility for alpha-Hydrastine. Following Lipinski's Rule of Five, alpha-Hydrastine has 0 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of alpha-Hydrastine?

The CAS number of alpha-Hydrastine is 4370-85-8.

What is the molecular formula of alpha-Hydrastine?

The molecular formula of alpha-Hydrastine is C21H21NO6.

What is the molecular weight of alpha-Hydrastine?

The molecular weight of alpha-Hydrastine is 383.14 g/mol.

Where can I buy alpha-Hydrastine?

You can request a quote for alpha-Hydrastine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for alpha-Hydrastine?

Yes, KEHONG BIO provides custom synthesis services for alpha-Hydrastine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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