6-Fluoro-2-(4-fluorophenyl)quinazoline-4-thiol
TL;DR: 6-Fluoro-2-(4-fluorophenyl)quinazoline-4-thiol (CAS 436092-69-2) is a chemical compound with molecular formula C14H8F2N2S and molecular weight 274.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-fluoro-2-(4-fluorophenyl)-1H-quinazoline-4-thione
Also Known As: 6-fluoro-2-(4-fluorophenyl)quinazoline-4-thiol, 6-fluoro-2-(4-fluorophenyl)-1H-quinazoline-4-thione, N/A
| Molecular Formula | C14H8F2N2S |
|---|---|
| Molecular Weight | 274.04 g/mol |
| LogP | 4.23759 |
| Topological Polar Surface Area | 28.68 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 274.03763 |
| Heavy Atoms | 19 |
| Complexity | 809.78406 |
Chemical Identifiers
| CAS Number | 436092-69-2 |
|---|---|
| SMILES | C1=CC(=CC=C1C2=NC(=S)C3=C(N2)C=CC(=C3)F)F |
Product Overview
6-Fluoro-2-(4-fluorophenyl)quinazoline-4-thiol (CAS 436092-69-2), with molecular formula C14H8F2N2S and molecular weight 274.04 g/mol. IUPAC: 6-fluoro-2-(4-fluorophenyl)-1H-quinazoline-4-thione.
Chemical Property Profile of 6-Fluoro-2-(4-fluorophenyl)quinazoline-4-thiol
Property Insights of 6-Fluoro-2-(4-fluorophenyl)quinazoline-4-thiol
The XLogP value of 4.23759 indicates that 6-Fluoro-2-(4-fluorophenyl)quinazoline-4-thiol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 28.68 Ų, 6-Fluoro-2-(4-fluorophenyl)quinazoline-4-thiol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6-Fluoro-2-(4-fluorophenyl)quinazoline-4-thiol has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-Fluoro-2-(4-fluorophenyl)quinazoline-4-thiol?
The CAS number of 6-Fluoro-2-(4-fluorophenyl)quinazoline-4-thiol is 436092-69-2.
What is the molecular formula of 6-Fluoro-2-(4-fluorophenyl)quinazoline-4-thiol?
The molecular formula of 6-Fluoro-2-(4-fluorophenyl)quinazoline-4-thiol is C14H8F2N2S.
What is the molecular weight of 6-Fluoro-2-(4-fluorophenyl)quinazoline-4-thiol?
The molecular weight of 6-Fluoro-2-(4-fluorophenyl)quinazoline-4-thiol is 274.04 g/mol.
Where can I buy 6-Fluoro-2-(4-fluorophenyl)quinazoline-4-thiol?
You can request a quote for 6-Fluoro-2-(4-fluorophenyl)quinazoline-4-thiol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-Fluoro-2-(4-fluorophenyl)quinazoline-4-thiol?
Yes, KEHONG BIO provides custom synthesis services for 6-Fluoro-2-(4-fluorophenyl)quinazoline-4-thiol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.