21-Deoxybetamethasone 17-propionate
TL;DR: 21-Deoxybetamethasone 17-propionate (CAS 4351-48-8) is a chemical compound with molecular formula C25H33FO5 and molecular weight 432.23 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[(8S,9R,10S,11S,13S,14S,16S,17R)-17-acetyl-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate
Also Known As: 21-Deoxybetamethasone 17-propionate, Clobetasol Propionate EP Impurity H, DOXIBETASOL PROPIONATE, 21-Deschloro Clobetasol 17-Propionate, DOXIBETASOL 17-PROPIONATE
| Molecular Formula | C25H33FO5 |
|---|---|
| Molecular Weight | 432.23 g/mol |
| LogP | 3.1 |
| Topological Polar Surface Area | 80.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 432.2312 |
| Heavy Atoms | 31 |
| Complexity | 908.0 |
Chemical Identifiers
| CAS Number | 4351-48-8 |
|---|---|
| SMILES | CCC(=O)O[C@@]1([C@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)F)O)C)C)C(=O)C |
| InChIKey | ZAQGQQMIBBCIRM-RDEWRQEPSA-N |
Product Overview
21-Deoxybetamethasone 17-propionate (CAS 4351-48-8), with molecular formula C25H33FO5 and molecular weight 432.23 g/mol. IUPAC: [(8S,9R,10S,11S,13S,14S,16S,17R)-17-acetyl-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate.
Chemical Property Profile of 21-Deoxybetamethasone 17-propionate
Property Insights of 21-Deoxybetamethasone 17-propionate
The XLogP value of 3.1 indicates that 21-Deoxybetamethasone 17-propionate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 80.7 Ų falls within the moderate polarity range, balancing permeability and solubility for 21-Deoxybetamethasone 17-propionate. Following Lipinski's Rule of Five, 21-Deoxybetamethasone 17-propionate has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 21-Deoxybetamethasone 17-propionate?
The CAS number of 21-Deoxybetamethasone 17-propionate is 4351-48-8.
What is the molecular formula of 21-Deoxybetamethasone 17-propionate?
The molecular formula of 21-Deoxybetamethasone 17-propionate is C25H33FO5.
What is the molecular weight of 21-Deoxybetamethasone 17-propionate?
The molecular weight of 21-Deoxybetamethasone 17-propionate is 432.23 g/mol.
Where can I buy 21-Deoxybetamethasone 17-propionate?
You can request a quote for 21-Deoxybetamethasone 17-propionate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 21-Deoxybetamethasone 17-propionate?
Yes, KEHONG BIO provides custom synthesis services for 21-Deoxybetamethasone 17-propionate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.