AF-399/40960407 structure

AF-399/40960407

TL;DR: AF-399/40960407 (CAS 433327-67-4) is a chemical compound with molecular formula C20H18FN3O4S and molecular weight 415.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-(4-fluorophenyl)-5-(3,4,5-trimethoxyphenyl)-5,6-dihydro-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one

Also Known As: AF-399/40960407, 2-(4-fluorophenyl)-5-(3,4,5-trimethoxyphenyl)-5,6-dihydro-7H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one, 2-(4-fluorophenyl)-5-(3,4,5-trimethoxyphenyl)-5,6-dihydro-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one, 2-(4-FLUOROPHENYL)-5-(3,4,5-TRIMETHOXYPHENYL)-5H,6H,7H-[1,2,4]TRIAZOLO[3,2-B][1,3]THIAZIN-7-ONE, 2-(4-fluorophenyl)-5-(3,4,5-trimethoxyphenyl)-5H,6H-1,2,4-triazolo[5,1-b]1,3-t hiazaperhydroin-7-one

CAS: 433327-67-4
Molecular Formula C20H18FN3O4S
Molecular Weight 415.10 g/mol
LogP 3.9873
Topological Polar Surface Area 75.47 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 7
Rotatable Bonds 5
Exact Mass 415.10022
Heavy Atoms 29
Complexity 1043.0834

Chemical Identifiers

CAS Number 433327-67-4
SMILES COC1=CC(=CC(=C1OC)OC)C2CC(=O)N3C(=NC(=N3)C4=CC=C(C=C4)F)S2

Product Overview

AF-399/40960407 (CAS 433327-67-4), with molecular formula C20H18FN3O4S and molecular weight 415.10 g/mol. IUPAC: 2-(4-fluorophenyl)-5-(3,4,5-trimethoxyphenyl)-5,6-dihydro-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of AF-399/40960407

XLogP
3.9873
TPSA (Topological Polar Surface Area)
75.47
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
7
Rotatable Bonds
5
Heavy Atoms
29
Complexity
1043.0834
Exact Mass
415.10022
Monoisotopic Mass
415.10022
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of AF-399/40960407

The XLogP value of 3.9873 indicates that AF-399/40960407 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 75.47 Ų falls within the moderate polarity range, balancing permeability and solubility for AF-399/40960407. Following Lipinski's Rule of Five, AF-399/40960407 has 0 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of AF-399/40960407?

The CAS number of AF-399/40960407 is 433327-67-4.

What is the molecular formula of AF-399/40960407?

The molecular formula of AF-399/40960407 is C20H18FN3O4S.

What is the molecular weight of AF-399/40960407?

The molecular weight of AF-399/40960407 is 415.10 g/mol.

Where can I buy AF-399/40960407?

You can request a quote for AF-399/40960407 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for AF-399/40960407?

Yes, KEHONG BIO provides custom synthesis services for AF-399/40960407 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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