![(E)-N-[(3-chloro-4-pyrrolidin-1-ylphenyl)carbamothioyl]-3-phenylprop-2-enamide structure](/static/products/4320/432001-51-9.webp)
(E)-N-[(3-chloro-4-pyrrolidin-1-ylphenyl)carbamothioyl]-3-phenylprop-2-enamide
TL;DR: (E)-N-[(3-chloro-4-pyrrolidin-1-ylphenyl)carbamothioyl]-3-phenylprop-2-enamide (CAS 432001-51-9) is a chemical compound with molecular formula C20H20ClN3OS and molecular weight 385.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-N-[(3-chloro-4-pyrrolidin-1-ylphenyl)carbamothioyl]-3-phenylprop-2-enamide
Also Known As: (2E)-N-{[3-chloro-4-(pyrrolidin-1-yl)phenyl]carbamothioyl}-3-phenylprop-2-enamide, (E)-N-[(3-chloro-4-pyrrolidin-1-ylphenyl)carbamothioyl]-3-phenylprop-2-enamide
| Molecular Formula | C20H20ClN3OS |
|---|---|
| Molecular Weight | 385.10 g/mol |
| LogP | 4.4666 |
| Topological Polar Surface Area | 44.37 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 385.10156 |
| Heavy Atoms | 26 |
| Complexity | 817.0609 |
Chemical Identifiers
| CAS Number | 432001-51-9 |
|---|---|
| SMILES | C1CCN(C1)C2=C(C=C(C=C2)NC(=S)NC(=O)/C=C/C3=CC=CC=C3)Cl |
Product Overview
(E)-N-[(3-chloro-4-pyrrolidin-1-ylphenyl)carbamothioyl]-3-phenylprop-2-enamide (CAS 432001-51-9), with molecular formula C20H20ClN3OS and molecular weight 385.10 g/mol. IUPAC: (E)-N-[(3-chloro-4-pyrrolidin-1-ylphenyl)carbamothioyl]-3-phenylprop-2-enamide.
Chemical Property Profile of (E)-N-[(3-chloro-4-pyrrolidin-1-ylphenyl)carbamothioyl]-3-phenylprop-2-enamide
Property Insights of (E)-N-[(3-chloro-4-pyrrolidin-1-ylphenyl)carbamothioyl]-3-phenylprop-2-enamide
The XLogP value of 4.4666 indicates that (E)-N-[(3-chloro-4-pyrrolidin-1-ylphenyl)carbamothioyl]-3-phenylprop-2-enamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 44.37 Ų, (E)-N-[(3-chloro-4-pyrrolidin-1-ylphenyl)carbamothioyl]-3-phenylprop-2-enamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-N-[(3-chloro-4-pyrrolidin-1-ylphenyl)carbamothioyl]-3-phenylprop-2-enamide has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-N-[(3-chloro-4-pyrrolidin-1-ylphenyl)carbamothioyl]-3-phenylprop-2-enamide?
The CAS number of (E)-N-[(3-chloro-4-pyrrolidin-1-ylphenyl)carbamothioyl]-3-phenylprop-2-enamide is 432001-51-9.
What is the molecular formula of (E)-N-[(3-chloro-4-pyrrolidin-1-ylphenyl)carbamothioyl]-3-phenylprop-2-enamide?
The molecular formula of (E)-N-[(3-chloro-4-pyrrolidin-1-ylphenyl)carbamothioyl]-3-phenylprop-2-enamide is C20H20ClN3OS.
What is the molecular weight of (E)-N-[(3-chloro-4-pyrrolidin-1-ylphenyl)carbamothioyl]-3-phenylprop-2-enamide?
The molecular weight of (E)-N-[(3-chloro-4-pyrrolidin-1-ylphenyl)carbamothioyl]-3-phenylprop-2-enamide is 385.10 g/mol.
Where can I buy (E)-N-[(3-chloro-4-pyrrolidin-1-ylphenyl)carbamothioyl]-3-phenylprop-2-enamide?
You can request a quote for (E)-N-[(3-chloro-4-pyrrolidin-1-ylphenyl)carbamothioyl]-3-phenylprop-2-enamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-N-[(3-chloro-4-pyrrolidin-1-ylphenyl)carbamothioyl]-3-phenylprop-2-enamide?
Yes, KEHONG BIO provides custom synthesis services for (E)-N-[(3-chloro-4-pyrrolidin-1-ylphenyl)carbamothioyl]-3-phenylprop-2-enamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.