2-Methyl-9alpha-fluorohydrocortisone, (2R)-
TL;DR: 2-Methyl-9alpha-fluorohydrocortisone, (2R)- (CAS 432-34-8) is a chemical compound with molecular formula C22H31FO5 and molecular weight 394.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2R,8S,9R,10S,11S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-2,10,13-trimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
Also Known As: 2alpha-Methyl-9alpha-fluorocortisol, A-methyl-9, A-fluorocortisol, 3-hydroxy-3,3-diphenyl-propylamine, 3-Amino-1,1-diphenyl-propanol-(1)
| Molecular Formula | C22H31FO5 |
|---|---|
| Molecular Weight | 394.22 g/mol |
| LogP | 2.2 |
| Topological Polar Surface Area | 94.8 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 394.21555 |
| Heavy Atoms | 28 |
| Complexity | 764.0 |
Chemical Identifiers
| CAS Number | 432-34-8 |
|---|---|
| SMILES | C[C@@H]1C[C@]2(C(=CC1=O)CC[C@@H]3[C@@]2([C@H](C[C@]4([C@H]3CC[C@@]4(C(=O)CO)O)C)O)F)C |
| InChIKey | YUCOGNZKLOYCGL-CPEVGGJCSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
2-Methyl-9alpha-fluorohydrocortisone, (2R)- (CAS 432-34-8), with molecular formula C22H31FO5 and molecular weight 394.22 g/mol. IUPAC: (2R,8S,9R,10S,11S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-2,10,13-trimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one.
Chemical Property Profile of 2-Methyl-9alpha-fluorohydrocortisone, (2R)-
Property Insights of 2-Methyl-9alpha-fluorohydrocortisone, (2R)-
The XLogP value of 2.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-Methyl-9alpha-fluorohydrocortisone, (2R)-. The TPSA of 94.8 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-Methyl-9alpha-fluorohydrocortisone, (2R)-. Following Lipinski's Rule of Five, 2-Methyl-9alpha-fluorohydrocortisone, (2R)- has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-Methyl-9alpha-fluorohydrocortisone, (2R)-?
The CAS number of 2-Methyl-9alpha-fluorohydrocortisone, (2R)- is 432-34-8.
What is the molecular formula of 2-Methyl-9alpha-fluorohydrocortisone, (2R)-?
The molecular formula of 2-Methyl-9alpha-fluorohydrocortisone, (2R)- is C22H31FO5.
What is the molecular weight of 2-Methyl-9alpha-fluorohydrocortisone, (2R)-?
The molecular weight of 2-Methyl-9alpha-fluorohydrocortisone, (2R)- is 394.22 g/mol.
Where can I buy 2-Methyl-9alpha-fluorohydrocortisone, (2R)-?
You can request a quote for 2-Methyl-9alpha-fluorohydrocortisone, (2R)- directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-Methyl-9alpha-fluorohydrocortisone, (2R)-?
Yes, KEHONG BIO provides custom synthesis services for 2-Methyl-9alpha-fluorohydrocortisone, (2R)- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.