N-(3-chloro-4-pyrrolidin-1-ylphenyl)thiophene-2-carboxamide
TL;DR: N-(3-chloro-4-pyrrolidin-1-ylphenyl)thiophene-2-carboxamide (CAS 431996-71-3) is a chemical compound with molecular formula C15H15ClN2OS and molecular weight 306.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(3-chloro-4-pyrrolidin-1-ylphenyl)thiophene-2-carboxamide
Also Known As: BAS 06843267, N-(3-chloro-4-pyrrolidin-1-ylphenyl)thiophene-2-carboxamide, AP-970/41096889, N-[3-chloro-4-(1-pyrrolidinyl)phenyl]-2-thiophenecarboxamide, N-(3-chloro-4-pyrrolidino-phenyl)thiophene-2-carboxamide
| Molecular Formula | C15H15ClN2OS |
|---|---|
| Molecular Weight | 306.06 g/mol |
| LogP | 4.254 |
| Topological Polar Surface Area | 32.34 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 306.05936 |
| Heavy Atoms | 20 |
| Complexity | 606.341 |
Chemical Identifiers
| CAS Number | 431996-71-3 |
|---|---|
| SMILES | C1CCN(C1)C2=C(C=C(C=C2)NC(=O)C3=CC=CS3)Cl |
Product Overview
N-(3-chloro-4-pyrrolidin-1-ylphenyl)thiophene-2-carboxamide (CAS 431996-71-3), with molecular formula C15H15ClN2OS and molecular weight 306.06 g/mol. IUPAC: N-(3-chloro-4-pyrrolidin-1-ylphenyl)thiophene-2-carboxamide.
Chemical Property Profile of N-(3-chloro-4-pyrrolidin-1-ylphenyl)thiophene-2-carboxamide
Property Insights of N-(3-chloro-4-pyrrolidin-1-ylphenyl)thiophene-2-carboxamide
The XLogP value of 4.254 indicates that N-(3-chloro-4-pyrrolidin-1-ylphenyl)thiophene-2-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 32.34 Ų, N-(3-chloro-4-pyrrolidin-1-ylphenyl)thiophene-2-carboxamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(3-chloro-4-pyrrolidin-1-ylphenyl)thiophene-2-carboxamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(3-chloro-4-pyrrolidin-1-ylphenyl)thiophene-2-carboxamide?
The CAS number of N-(3-chloro-4-pyrrolidin-1-ylphenyl)thiophene-2-carboxamide is 431996-71-3.
What is the molecular formula of N-(3-chloro-4-pyrrolidin-1-ylphenyl)thiophene-2-carboxamide?
The molecular formula of N-(3-chloro-4-pyrrolidin-1-ylphenyl)thiophene-2-carboxamide is C15H15ClN2OS.
What is the molecular weight of N-(3-chloro-4-pyrrolidin-1-ylphenyl)thiophene-2-carboxamide?
The molecular weight of N-(3-chloro-4-pyrrolidin-1-ylphenyl)thiophene-2-carboxamide is 306.06 g/mol.
Where can I buy N-(3-chloro-4-pyrrolidin-1-ylphenyl)thiophene-2-carboxamide?
You can request a quote for N-(3-chloro-4-pyrrolidin-1-ylphenyl)thiophene-2-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(3-chloro-4-pyrrolidin-1-ylphenyl)thiophene-2-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for N-(3-chloro-4-pyrrolidin-1-ylphenyl)thiophene-2-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.