4-(1-Piperazinyl)-1-(2-thienylsulfonyl)-1H-indole
TL;DR: 4-(1-Piperazinyl)-1-(2-thienylsulfonyl)-1H-indole (CAS 431045-41-9) is a chemical compound with molecular formula C16H17N3O2S2 and molecular weight 347.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-piperazin-1-yl-1-thiophen-2-ylsulfonylindole
Also Known As: 4-piperazin-1-yl-1-thiophen-2-ylsulfonyl-indole, 4-(1-Piperazinyl)-1-(2-thienylsulfonyl)-1H-indole
| Molecular Formula | C16H17N3O2S2 |
|---|---|
| Molecular Weight | 347.08 g/mol |
| LogP | 2.3494 |
| Topological Polar Surface Area | 54.34 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 347.07623 |
| Heavy Atoms | 23 |
| Complexity | 923.55505 |
Chemical Identifiers
| CAS Number | 431045-41-9 |
|---|---|
| SMILES | C1CN(CCN1)C2=CC=CC3=C2C=CN3S(=O)(=O)C4=CC=CS4 |
Product Overview
4-(1-Piperazinyl)-1-(2-thienylsulfonyl)-1H-indole (CAS 431045-41-9), with molecular formula C16H17N3O2S2 and molecular weight 347.08 g/mol. IUPAC: 4-piperazin-1-yl-1-thiophen-2-ylsulfonylindole.
Chemical Property Profile of 4-(1-Piperazinyl)-1-(2-thienylsulfonyl)-1H-indole
Property Insights of 4-(1-Piperazinyl)-1-(2-thienylsulfonyl)-1H-indole
The XLogP value of 2.3494 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-(1-Piperazinyl)-1-(2-thienylsulfonyl)-1H-indole. With a topological polar surface area (TPSA) of 54.34 Ų, 4-(1-Piperazinyl)-1-(2-thienylsulfonyl)-1H-indole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-(1-Piperazinyl)-1-(2-thienylsulfonyl)-1H-indole has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(1-Piperazinyl)-1-(2-thienylsulfonyl)-1H-indole?
The CAS number of 4-(1-Piperazinyl)-1-(2-thienylsulfonyl)-1H-indole is 431045-41-9.
What is the molecular formula of 4-(1-Piperazinyl)-1-(2-thienylsulfonyl)-1H-indole?
The molecular formula of 4-(1-Piperazinyl)-1-(2-thienylsulfonyl)-1H-indole is C16H17N3O2S2.
What is the molecular weight of 4-(1-Piperazinyl)-1-(2-thienylsulfonyl)-1H-indole?
The molecular weight of 4-(1-Piperazinyl)-1-(2-thienylsulfonyl)-1H-indole is 347.08 g/mol.
Where can I buy 4-(1-Piperazinyl)-1-(2-thienylsulfonyl)-1H-indole?
You can request a quote for 4-(1-Piperazinyl)-1-(2-thienylsulfonyl)-1H-indole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(1-Piperazinyl)-1-(2-thienylsulfonyl)-1H-indole?
Yes, KEHONG BIO provides custom synthesis services for 4-(1-Piperazinyl)-1-(2-thienylsulfonyl)-1H-indole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.