1-Chloro-3,3,3-trifluoroacetone structure

1-Chloro-3,3,3-trifluoroacetone

TL;DR: 1-Chloro-3,3,3-trifluoroacetone (CAS 431-37-8) is a chemical compound with molecular formula C3H2ClF3O and molecular weight 145.97 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

3-chloro-1,1,1-trifluoropropan-2-one

Also Known As: 1-CHLORO-3,3,3-TRIFLUOROACETONE, 3-chloro-1,1,1-trifluoropropan-2-one, 3-chloro-1,1,1-trifluoroacetone, 3-chloro-1,1,1-trifluoropropanone, 2-Propanone, 3-chloro-1,1,1-trifluoro-

CAS: 431-37-8
Molecular Formula C3H2ClF3O
Molecular Weight 145.97 g/mol
LogP 1.3566
Topological Polar Surface Area 17.07 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 1
Rotatable Bonds 1
Exact Mass 145.97462
Heavy Atoms 8
Complexity 97.19188

Chemical Identifiers

CAS Number 431-37-8
SMILES C(C(=O)C(F)(F)F)Cl

Product Overview

1-Chloro-3,3,3-trifluoroacetone (CAS 431-37-8), with molecular formula C3H2ClF3O and molecular weight 145.97 g/mol. IUPAC: 3-chloro-1,1,1-trifluoropropan-2-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 1-Chloro-3,3,3-trifluoroacetone

XLogP
1.3566
TPSA (Topological Polar Surface Area)
17.07
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
1
Rotatable Bonds
1
Heavy Atoms
8
Complexity
97.19188
Exact Mass
145.97462
Monoisotopic Mass
145.97462
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 1-Chloro-3,3,3-trifluoroacetone

The XLogP value of 1.3566 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-Chloro-3,3,3-trifluoroacetone. With a topological polar surface area (TPSA) of 17.07 Ų, 1-Chloro-3,3,3-trifluoroacetone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-Chloro-3,3,3-trifluoroacetone has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 1-Chloro-3,3,3-trifluoroacetone?

The CAS number of 1-Chloro-3,3,3-trifluoroacetone is 431-37-8.

What is the molecular formula of 1-Chloro-3,3,3-trifluoroacetone?

The molecular formula of 1-Chloro-3,3,3-trifluoroacetone is C3H2ClF3O.

What is the molecular weight of 1-Chloro-3,3,3-trifluoroacetone?

The molecular weight of 1-Chloro-3,3,3-trifluoroacetone is 145.97 g/mol.

Where can I buy 1-Chloro-3,3,3-trifluoroacetone?

You can request a quote for 1-Chloro-3,3,3-trifluoroacetone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 1-Chloro-3,3,3-trifluoroacetone?

Yes, KEHONG BIO provides custom synthesis services for 1-Chloro-3,3,3-trifluoroacetone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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