RefChem:228868 structure

RefChem:228868

TL;DR: RefChem:228868 (CAS 43076-39-7) is a chemical compound with molecular formula C28H31ClFNO2 and molecular weight 467.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-(4-fluorophenyl)-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butan-1-one;hydrochloride

Also Known As: 1-Butanone, 1-(4-fluorophenyl)-4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)-, hydrochloride, 1-(4-Fluorophenyl)-4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)-1-butanone hydrochloride, 1-(4-fluorophenyl)-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butan-1-one hydrochloride, 4'-fluoro-4-[4-(alpha-hydroxy-alpha-phenylbenzyl)piperidino]butyrophenone hydrochloride, 1-(4-Fluorophenyl)-4-{4-[hydroxydi(phenyl)methyl]piperidin-1-yl}butan-1-one--hydrogen chloride (1/1)

CAS: 43076-39-7
Molecular Formula C28H31ClFNO2
Molecular Weight 467.20 g/mol
LogP 5.8585
Topological Polar Surface Area 40.5 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 4
Rotatable Bonds 8
Exact Mass 467.20273
Heavy Atoms 33
Complexity 550.0

Chemical Identifiers

CAS Number 43076-39-7
SMILES C1CN(CCC1C(C2=CC=CC=C2)(C3=CC=CC=C3)O)CCCC(=O)C4=CC=C(C=C4)F.Cl
InChIKey GAUUGHUPPXPIET-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.

Pharmaceutical Intermediates (5 patents)

Product Overview

RefChem:228868 (CAS 43076-39-7), with molecular formula C28H31ClFNO2 and molecular weight 467.20 g/mol. IUPAC: 1-(4-fluorophenyl)-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butan-1-one;hydrochloride.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of RefChem:228868

XLogP
5.8585
TPSA (Topological Polar Surface Area)
40.5
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
4
Rotatable Bonds
8
Heavy Atoms
33
Complexity
550.0
Exact Mass
467.20273
Monoisotopic Mass
467.20273
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of RefChem:228868

The XLogP value of 5.8585 indicates that RefChem:228868 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 40.5 Ų, RefChem:228868 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, RefChem:228868 has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of RefChem:228868?

The CAS number of RefChem:228868 is 43076-39-7.

What is the molecular formula of RefChem:228868?

The molecular formula of RefChem:228868 is C28H31ClFNO2.

What is the molecular weight of RefChem:228868?

The molecular weight of RefChem:228868 is 467.20 g/mol.

Where can I buy RefChem:228868?

You can request a quote for RefChem:228868 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for RefChem:228868?

Yes, KEHONG BIO provides custom synthesis services for RefChem:228868 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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