N-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)pivalamide
TL;DR: N-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)pivalamide (CAS 430454-70-9) is a chemical compound with molecular formula C11H12ClF3N2O and molecular weight 280.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2,2-dimethylpropanamide
Also Known As: N-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)pivalamide, N-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-2,2-dimethylpropanamide, SDCCGMLS-0042297.P002, J2.072.902C, N-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]pivalamide
| Molecular Formula | C11H12ClF3N2O |
|---|---|
| Molecular Weight | 280.06 g/mol |
| LogP | 3.7384 |
| Topological Polar Surface Area | 41.99 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 280.05902 |
| Heavy Atoms | 18 |
| Complexity | 466.3366 |
Chemical Identifiers
| CAS Number | 430454-70-9 |
|---|---|
| SMILES | CC(C)(C)C(=O)NC1=C(C=C(C=N1)C(F)(F)F)Cl |
Product Overview
N-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)pivalamide (CAS 430454-70-9), with molecular formula C11H12ClF3N2O and molecular weight 280.06 g/mol. IUPAC: N-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2,2-dimethylpropanamide.
Chemical Property Profile of N-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)pivalamide
Property Insights of N-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)pivalamide
The XLogP value of 3.7384 indicates that N-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)pivalamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.99 Ų, N-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)pivalamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)pivalamide has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)pivalamide?
The CAS number of N-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)pivalamide is 430454-70-9.
What is the molecular formula of N-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)pivalamide?
The molecular formula of N-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)pivalamide is C11H12ClF3N2O.
What is the molecular weight of N-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)pivalamide?
The molecular weight of N-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)pivalamide is 280.06 g/mol.
Where can I buy N-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)pivalamide?
You can request a quote for N-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)pivalamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)pivalamide?
Yes, KEHONG BIO provides custom synthesis services for N-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)pivalamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.