Dabigatran Ethyl Ester structure

Dabigatran Ethyl Ester

TL;DR: Dabigatran Ethyl Ester (CAS 429658-95-7) is a chemical compound with molecular formula C27H29N7O3 and molecular weight 499.23 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

ethyl 3-[[2-[(4-carbamimidoylanilino)methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoate

Also Known As: Dabigatran ethyl ester, Dabigatran (ethyl ester), Dabigatran ethyl AcOH Salt, Dabigatran-ethyl ester, 1-Methylpyrrolidin-3-ol

CAS: 429658-95-7
Molecular Formula C27H29N7O3
Molecular Weight 499.23 g/mol
LogP 2.4
Topological Polar Surface Area 139.0 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 7
Rotatable Bonds 11
Exact Mass 499.2332
Heavy Atoms 37
Complexity 788.0

Chemical Identifiers

CAS Number 429658-95-7
SMILES CCOC(=O)CCN(C1=CC=CC=N1)C(=O)C2=CC3=C(C=C2)N(C(=N3)CNC4=CC=C(C=C4)C(=N)N)C
InChIKey BGLLICFSSKPUMR-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (2 patents) Pharmaceutical Intermediates (2 patents)

Product Overview

Dabigatran Ethyl Ester (CAS 429658-95-7), with molecular formula C27H29N7O3 and molecular weight 499.23 g/mol. IUPAC: ethyl 3-[[2-[(4-carbamimidoylanilino)methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Dabigatran Ethyl Ester

XLogP
2.4
TPSA (Topological Polar Surface Area)
139.0
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
7
Rotatable Bonds
11
Heavy Atoms
37
Complexity
788.0
Exact Mass
499.2332
Monoisotopic Mass
499.2332
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Dabigatran Ethyl Ester

The XLogP value of 2.4 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Dabigatran Ethyl Ester. The TPSA of 139.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Dabigatran Ethyl Ester. Following Lipinski's Rule of Five, Dabigatran Ethyl Ester has 3 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Dabigatran Ethyl Ester?

The CAS number of Dabigatran Ethyl Ester is 429658-95-7.

What is the molecular formula of Dabigatran Ethyl Ester?

The molecular formula of Dabigatran Ethyl Ester is C27H29N7O3.

What is the molecular weight of Dabigatran Ethyl Ester?

The molecular weight of Dabigatran Ethyl Ester is 499.23 g/mol.

Where can I buy Dabigatran Ethyl Ester?

You can request a quote for Dabigatran Ethyl Ester directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Dabigatran Ethyl Ester?

Yes, KEHONG BIO provides custom synthesis services for Dabigatran Ethyl Ester and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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