2-(3-indolylidene)-4-(4-methylphenyl)-3H-thiazole
TL;DR: 2-(3-indolylidene)-4-(4-methylphenyl)-3H-thiazole (CAS 429647-89-2) is a chemical compound with molecular formula C18H14N2S and molecular weight 290.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(1H-indol-3-yl)-4-(4-methylphenyl)-1,3-thiazole
Also Known As: 2-(3-indolylidene)-4-(4-methylphenyl)-3H-thiazole, 2-(1H-indol-3-yl)-4-(4-methylphenyl)-1,3-thiazole, 2-(1H-indol-3-yl)-4-(p-tolyl)thiazole, 3-[4-(4-methylphenyl)-1,3-thiazol-2-yl]-1H-indole, AP-048/15614142
| Molecular Formula | C18H14N2S |
|---|---|
| Molecular Weight | 290.09 g/mol |
| LogP | 4.8 |
| Topological Polar Surface Area | 56.9 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 290.08777 |
| Heavy Atoms | 21 |
| Complexity | 353.0 |
Chemical Identifiers
| CAS Number | 429647-89-2 |
|---|---|
| SMILES | CC1=CC=C(C=C1)C2=CSC(=N2)C3=CNC4=CC=CC=C43 |
| InChIKey | MVNXSBSNUVMBEK-UHFFFAOYSA-N |
Product Overview
2-(3-indolylidene)-4-(4-methylphenyl)-3H-thiazole (CAS 429647-89-2), with molecular formula C18H14N2S and molecular weight 290.09 g/mol. IUPAC: 2-(1H-indol-3-yl)-4-(4-methylphenyl)-1,3-thiazole.
Chemical Property Profile of 2-(3-indolylidene)-4-(4-methylphenyl)-3H-thiazole
Property Insights of 2-(3-indolylidene)-4-(4-methylphenyl)-3H-thiazole
The XLogP value of 4.8 indicates that 2-(3-indolylidene)-4-(4-methylphenyl)-3H-thiazole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 56.9 Ų, 2-(3-indolylidene)-4-(4-methylphenyl)-3H-thiazole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-(3-indolylidene)-4-(4-methylphenyl)-3H-thiazole has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-(3-indolylidene)-4-(4-methylphenyl)-3H-thiazole?
The CAS number of 2-(3-indolylidene)-4-(4-methylphenyl)-3H-thiazole is 429647-89-2.
What is the molecular formula of 2-(3-indolylidene)-4-(4-methylphenyl)-3H-thiazole?
The molecular formula of 2-(3-indolylidene)-4-(4-methylphenyl)-3H-thiazole is C18H14N2S.
What is the molecular weight of 2-(3-indolylidene)-4-(4-methylphenyl)-3H-thiazole?
The molecular weight of 2-(3-indolylidene)-4-(4-methylphenyl)-3H-thiazole is 290.09 g/mol.
Where can I buy 2-(3-indolylidene)-4-(4-methylphenyl)-3H-thiazole?
You can request a quote for 2-(3-indolylidene)-4-(4-methylphenyl)-3H-thiazole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-(3-indolylidene)-4-(4-methylphenyl)-3H-thiazole?
Yes, KEHONG BIO provides custom synthesis services for 2-(3-indolylidene)-4-(4-methylphenyl)-3H-thiazole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.