6-(4-Fluorophenyl)-5-(4-methylphenoxy)-4-phenylpyrimidin-2(1H)-one
TL;DR: 6-(4-Fluorophenyl)-5-(4-methylphenoxy)-4-phenylpyrimidin-2(1H)-one (CAS 42919-57-3) is a chemical compound with molecular formula C23H17FN2O2 and molecular weight 372.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-(4-fluorophenyl)-5-(4-methylphenoxy)-4-phenyl-1H-pyrimidin-2-one
Also Known As: 5- -4-phenyl-6- -2 -pyrimidinone, 2(1H)-Pyrimidinone, 4-(4-fluorophenyl)-5-(4-methylphenoxy)-6-phenyl-, 6-(4-Fluorophenyl)-5-(4-methylphenoxy)-4-phenylpyrimidin-2(1H)-one, 4-(4-Fluorophenyl)-5-(4-methylphenoxy)-6-phenyl-2-pyrimidinol #, 2-Oxo-5-(4-tolyloxy)-4-phenyl-6-(4-fluorophenyl)-1,2-dihydropyrimidine
| Molecular Formula | C23H17FN2O2 |
|---|---|
| Molecular Weight | 372.13 g/mol |
| LogP | 5.1 |
| Topological Polar Surface Area | 50.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 372.1274 |
| Heavy Atoms | 28 |
| Complexity | 623.0 |
Chemical Identifiers
| CAS Number | 42919-57-3 |
|---|---|
| SMILES | CC1=CC=C(C=C1)OC2=C(NC(=O)N=C2C3=CC=CC=C3)C4=CC=C(C=C4)F |
| InChIKey | IHKPZAIQADXLIZ-UHFFFAOYSA-N |
Product Overview
6-(4-Fluorophenyl)-5-(4-methylphenoxy)-4-phenylpyrimidin-2(1H)-one (CAS 42919-57-3), with molecular formula C23H17FN2O2 and molecular weight 372.13 g/mol. IUPAC: 6-(4-fluorophenyl)-5-(4-methylphenoxy)-4-phenyl-1H-pyrimidin-2-one.
Chemical Property Profile of 6-(4-Fluorophenyl)-5-(4-methylphenoxy)-4-phenylpyrimidin-2(1H)-one
Property Insights of 6-(4-Fluorophenyl)-5-(4-methylphenoxy)-4-phenylpyrimidin-2(1H)-one
The XLogP value of 5.1 indicates that 6-(4-Fluorophenyl)-5-(4-methylphenoxy)-4-phenylpyrimidin-2(1H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 50.7 Ų, 6-(4-Fluorophenyl)-5-(4-methylphenoxy)-4-phenylpyrimidin-2(1H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6-(4-Fluorophenyl)-5-(4-methylphenoxy)-4-phenylpyrimidin-2(1H)-one has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-(4-Fluorophenyl)-5-(4-methylphenoxy)-4-phenylpyrimidin-2(1H)-one?
The CAS number of 6-(4-Fluorophenyl)-5-(4-methylphenoxy)-4-phenylpyrimidin-2(1H)-one is 42919-57-3.
What is the molecular formula of 6-(4-Fluorophenyl)-5-(4-methylphenoxy)-4-phenylpyrimidin-2(1H)-one?
The molecular formula of 6-(4-Fluorophenyl)-5-(4-methylphenoxy)-4-phenylpyrimidin-2(1H)-one is C23H17FN2O2.
What is the molecular weight of 6-(4-Fluorophenyl)-5-(4-methylphenoxy)-4-phenylpyrimidin-2(1H)-one?
The molecular weight of 6-(4-Fluorophenyl)-5-(4-methylphenoxy)-4-phenylpyrimidin-2(1H)-one is 372.13 g/mol.
Where can I buy 6-(4-Fluorophenyl)-5-(4-methylphenoxy)-4-phenylpyrimidin-2(1H)-one?
You can request a quote for 6-(4-Fluorophenyl)-5-(4-methylphenoxy)-4-phenylpyrimidin-2(1H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-(4-Fluorophenyl)-5-(4-methylphenoxy)-4-phenylpyrimidin-2(1H)-one?
Yes, KEHONG BIO provides custom synthesis services for 6-(4-Fluorophenyl)-5-(4-methylphenoxy)-4-phenylpyrimidin-2(1H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.