N-(3,4-difluorophenyl)-3-(4-phenylpiperazin-1-yl)propanamide
TL;DR: N-(3,4-difluorophenyl)-3-(4-phenylpiperazin-1-yl)propanamide (CAS 428853-59-2) is a chemical compound with molecular formula C19H21F2N3O and molecular weight 345.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(3,4-difluorophenyl)-3-(4-phenylpiperazin-1-yl)propanamide
Also Known As: N-(3,4-difluorophenyl)-3-(4-phenylpiperazin-1-yl)propanamide, AT-057/43314271, N-(3,4-difluorophenyl)-3-(4-phenyl-1-piperazinyl)propanamide, N-(3,4-difluorophenyl)-3-(4-phenylpiperazinyl)propanamide
| Molecular Formula | C19H21F2N3O |
|---|---|
| Molecular Weight | 345.17 g/mol |
| LogP | 3.1156 |
| Topological Polar Surface Area | 35.58 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 345.16528 |
| Heavy Atoms | 25 |
| Complexity | 715.8641 |
Chemical Identifiers
| CAS Number | 428853-59-2 |
|---|---|
| SMILES | C1CN(CCN1CCC(=O)NC2=CC(=C(C=C2)F)F)C3=CC=CC=C3 |
Product Overview
N-(3,4-difluorophenyl)-3-(4-phenylpiperazin-1-yl)propanamide (CAS 428853-59-2), with molecular formula C19H21F2N3O and molecular weight 345.17 g/mol. IUPAC: N-(3,4-difluorophenyl)-3-(4-phenylpiperazin-1-yl)propanamide.
Chemical Property Profile of N-(3,4-difluorophenyl)-3-(4-phenylpiperazin-1-yl)propanamide
Property Insights of N-(3,4-difluorophenyl)-3-(4-phenylpiperazin-1-yl)propanamide
The XLogP value of 3.1156 indicates that N-(3,4-difluorophenyl)-3-(4-phenylpiperazin-1-yl)propanamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 35.58 Ų, N-(3,4-difluorophenyl)-3-(4-phenylpiperazin-1-yl)propanamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(3,4-difluorophenyl)-3-(4-phenylpiperazin-1-yl)propanamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(3,4-difluorophenyl)-3-(4-phenylpiperazin-1-yl)propanamide?
The CAS number of N-(3,4-difluorophenyl)-3-(4-phenylpiperazin-1-yl)propanamide is 428853-59-2.
What is the molecular formula of N-(3,4-difluorophenyl)-3-(4-phenylpiperazin-1-yl)propanamide?
The molecular formula of N-(3,4-difluorophenyl)-3-(4-phenylpiperazin-1-yl)propanamide is C19H21F2N3O.
What is the molecular weight of N-(3,4-difluorophenyl)-3-(4-phenylpiperazin-1-yl)propanamide?
The molecular weight of N-(3,4-difluorophenyl)-3-(4-phenylpiperazin-1-yl)propanamide is 345.17 g/mol.
Where can I buy N-(3,4-difluorophenyl)-3-(4-phenylpiperazin-1-yl)propanamide?
You can request a quote for N-(3,4-difluorophenyl)-3-(4-phenylpiperazin-1-yl)propanamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(3,4-difluorophenyl)-3-(4-phenylpiperazin-1-yl)propanamide?
Yes, KEHONG BIO provides custom synthesis services for N-(3,4-difluorophenyl)-3-(4-phenylpiperazin-1-yl)propanamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.