Lopirazepam
TL;DR: Lopirazepam (CAS 42863-81-0) is a chemical compound with molecular formula C14H9Cl2N3O2 and molecular weight 321.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydropyrido[3,2-e][1,4]diazepin-2-one
Also Known As: Lopirazepam, Lopirazepamum, Lopirazepam [INN], (+)-Lopirazepam, (-)-Lopirazepam
| Molecular Formula | C14H9Cl2N3O2 |
|---|---|
| Molecular Weight | 321.01 g/mol |
| LogP | 2.7 |
| Topological Polar Surface Area | 74.6 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 321.00717 |
| Heavy Atoms | 21 |
| Complexity | 446.0 |
Chemical Identifiers
| CAS Number | 42863-81-0 |
|---|---|
| SMILES | C1=CC=C(C(=C1)C2=NC(C(=O)NC3=C2N=C(C=C3)Cl)O)Cl |
| InChIKey | JEJOFYTVMFVKQA-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 6 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Lopirazepam (CAS 42863-81-0), with molecular formula C14H9Cl2N3O2 and molecular weight 321.01 g/mol. IUPAC: 7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydropyrido[3,2-e][1,4]diazepin-2-one.
Chemical Property Profile of Lopirazepam
Property Insights of Lopirazepam
The XLogP value of 2.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Lopirazepam. The TPSA of 74.6 Ų falls within the moderate polarity range, balancing permeability and solubility for Lopirazepam. Following Lipinski's Rule of Five, Lopirazepam has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Lopirazepam?
The CAS number of Lopirazepam is 42863-81-0.
What is the molecular formula of Lopirazepam?
The molecular formula of Lopirazepam is C14H9Cl2N3O2.
What is the molecular weight of Lopirazepam?
The molecular weight of Lopirazepam is 321.01 g/mol.
Where can I buy Lopirazepam?
You can request a quote for Lopirazepam directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Lopirazepam?
Yes, KEHONG BIO provides custom synthesis services for Lopirazepam and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.