AH-487/15274288
TL;DR: AH-487/15274288 (CAS 428472-69-9) is a chemical compound with molecular formula C24H21F3N2O3S and molecular weight 474.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[2-(3,4-dihydro-1H-isoquinolin-2-yl)-2-oxoethyl]-N-[3-(trifluoromethyl)phenyl]benzenesulfonamide
Also Known As: AH-487/15274288, N-[2-(3,4-dihydro-1H-isoquinolin-2-yl)-2-oxoethyl]-N-[3-(trifluoromethyl)phenyl]benzenesulfonamide, N-[2-(3,4-dihydro-2(1H)-isoquinolinyl)-2-oxoethyl]-N-[3-(trifluoromethyl)phenyl]benzenesulfonamide, N-[2-(3,4-dihydroisoquinolin-2(1H)-yl)-2-oxoethyl]-N-[3-(trifluoromethyl)phenyl]benzenesulfonamide
| Molecular Formula | C24H21F3N2O3S |
|---|---|
| Molecular Weight | 474.12 g/mol |
| LogP | 4.4856 |
| Topological Polar Surface Area | 57.69 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 474.1225 |
| Heavy Atoms | 33 |
| Complexity | 1261.201 |
Chemical Identifiers
| CAS Number | 428472-69-9 |
|---|---|
| SMILES | C1CN(CC2=CC=CC=C21)C(=O)CN(C3=CC=CC(=C3)C(F)(F)F)S(=O)(=O)C4=CC=CC=C4 |
Product Overview
AH-487/15274288 (CAS 428472-69-9), with molecular formula C24H21F3N2O3S and molecular weight 474.12 g/mol. IUPAC: N-[2-(3,4-dihydro-1H-isoquinolin-2-yl)-2-oxoethyl]-N-[3-(trifluoromethyl)phenyl]benzenesulfonamide.
Chemical Property Profile of AH-487/15274288
Property Insights of AH-487/15274288
The XLogP value of 4.4856 indicates that AH-487/15274288 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 57.69 Ų, AH-487/15274288 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, AH-487/15274288 has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AH-487/15274288?
The CAS number of AH-487/15274288 is 428472-69-9.
What is the molecular formula of AH-487/15274288?
The molecular formula of AH-487/15274288 is C24H21F3N2O3S.
What is the molecular weight of AH-487/15274288?
The molecular weight of AH-487/15274288 is 474.12 g/mol.
Where can I buy AH-487/15274288?
You can request a quote for AH-487/15274288 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AH-487/15274288?
Yes, KEHONG BIO provides custom synthesis services for AH-487/15274288 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.