6-Chlorouracil
TL;DR: 6-Chlorouracil (CAS 4270-27-3) is a chemical compound with molecular formula C4H3ClN2O2 and molecular weight 145.99 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-chloro-1H-pyrimidine-2,4-dione
Also Known As: 6-Chlorouracil, 6-Chloropyrimidine-2,4-diol, 4-Chlorouracil, 6-chloropyrimidine-2,4(1H,3H)-dione, 6-chloro-uracil
| Molecular Formula | C4H3ClN2O2 |
|---|---|
| Molecular Weight | 145.99 g/mol |
| LogP | -0.3 |
| Topological Polar Surface Area | 58.2 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 0 |
| Exact Mass | 145.98831 |
| Heavy Atoms | 9 |
| Complexity | 199.0 |
Chemical Identifiers
| CAS Number | 4270-27-3 |
|---|---|
| SMILES | C1=C(NC(=O)NC1=O)Cl |
| InChIKey | PKUFNWPSFCOSLU-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 7 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
6-Chlorouracil (CAS 4270-27-3), with molecular formula C4H3ClN2O2 and molecular weight 145.99 g/mol. IUPAC: 6-chloro-1H-pyrimidine-2,4-dione.
Chemical Property Profile of 6-Chlorouracil
Property Insights of 6-Chlorouracil
The XLogP value of -0.3 indicates that 6-Chlorouracil is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. With a topological polar surface area (TPSA) of 58.2 Ų, 6-Chlorouracil exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6-Chlorouracil has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-Chlorouracil?
The CAS number of 6-Chlorouracil is 4270-27-3.
What is the molecular formula of 6-Chlorouracil?
The molecular formula of 6-Chlorouracil is C4H3ClN2O2.
What is the molecular weight of 6-Chlorouracil?
The molecular weight of 6-Chlorouracil is 145.99 g/mol.
Where can I buy 6-Chlorouracil?
You can request a quote for 6-Chlorouracil directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-Chlorouracil?
Yes, KEHONG BIO provides custom synthesis services for 6-Chlorouracil and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.