Teclothiazide
TL;DR: Teclothiazide (CAS 4267-05-4) is a chemical compound with molecular formula C8H7Cl4N3O4S2 and molecular weight 412.86 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-chloro-1,1-dioxo-3-(trichloromethyl)-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide
Also Known As: Teclothiazide, Teclothiazidum, teclothiazid, teclotiazida, Teclotiazide
| Molecular Formula | C8H7Cl4N3O4S2 |
|---|---|
| Molecular Weight | 412.86 g/mol |
| LogP | 0.5 |
| Topological Polar Surface Area | 135.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 1 |
| Exact Mass | 414.86026 |
| Heavy Atoms | 21 |
| Complexity | 609.0 |
Chemical Identifiers
| CAS Number | 4267-05-4 |
|---|---|
| SMILES | C1=C2C(=CC(=C1Cl)S(=O)(=O)N)S(=O)(=O)NC(N2)C(Cl)(Cl)Cl |
| InChIKey | GUTZRTRUIMWMJZ-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 7 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Teclothiazide (CAS 4267-05-4), with molecular formula C8H7Cl4N3O4S2 and molecular weight 412.86 g/mol. IUPAC: 6-chloro-1,1-dioxo-3-(trichloromethyl)-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide.
Chemical Property Profile of Teclothiazide
Property Insights of Teclothiazide
The XLogP value of 0.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Teclothiazide. The TPSA of 135.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Teclothiazide. Following Lipinski's Rule of Five, Teclothiazide has 3 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Teclothiazide?
The CAS number of Teclothiazide is 4267-05-4.
What is the molecular formula of Teclothiazide?
The molecular formula of Teclothiazide is C8H7Cl4N3O4S2.
What is the molecular weight of Teclothiazide?
The molecular weight of Teclothiazide is 412.86 g/mol.
Where can I buy Teclothiazide?
You can request a quote for Teclothiazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Teclothiazide?
Yes, KEHONG BIO provides custom synthesis services for Teclothiazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.