![1-{5-[(E)-2-(2-chlorophenyl)ethenyl]-1,3,4-thiadiazol-2-yl}-3-(4-fluorophenyl)urea structure](/static/products/4262/426247-74-7.webp)
1-{5-[(E)-2-(2-chlorophenyl)ethenyl]-1,3,4-thiadiazol-2-yl}-3-(4-fluorophenyl)urea
TL;DR: 1-{5-[(E)-2-(2-chlorophenyl)ethenyl]-1,3,4-thiadiazol-2-yl}-3-(4-fluorophenyl)urea (CAS 426247-74-7) is a chemical compound with molecular formula C17H12ClFN4OS and molecular weight 374.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[5-[(E)-2-(2-chlorophenyl)ethenyl]-1,3,4-thiadiazol-2-yl]-3-(4-fluorophenyl)urea
Also Known As: 1-{5-[(E)-2-(2-chlorophenyl)ethenyl]-1,3,4-thiadiazol-2-yl}-3-(4-fluorophenyl)urea, 1-[5-[(E)-2-(2-chlorophenyl)ethenyl]-1,3,4-thiadiazol-2-yl]-3-(4-fluorophenyl)urea, (E)-1-(5-(2-chlorostyryl)-1,3,4-thiadiazol-2-yl)-3-(4-fluorophenyl)urea, 1-[(2Z)-5-[(E)-2-(2-chlorophenyl)ethenyl]-1,3,4-thiadiazol-2(3H)-ylidene]-3-(4-fluorophenyl)urea, Cambridge id 6373578
| Molecular Formula | C17H12ClFN4OS |
|---|---|
| Molecular Weight | 374.04 g/mol |
| LogP | 5.145 |
| Topological Polar Surface Area | 66.91 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 374.04044 |
| Heavy Atoms | 25 |
| Complexity | 911.0211 |
Chemical Identifiers
| CAS Number | 426247-74-7 |
|---|---|
| SMILES | C1=CC=C(C(=C1)/C=C/C2=NN=C(S2)NC(=O)NC3=CC=C(C=C3)F)Cl |
Product Overview
1-{5-[(E)-2-(2-chlorophenyl)ethenyl]-1,3,4-thiadiazol-2-yl}-3-(4-fluorophenyl)urea (CAS 426247-74-7), with molecular formula C17H12ClFN4OS and molecular weight 374.04 g/mol. IUPAC: 1-[5-[(E)-2-(2-chlorophenyl)ethenyl]-1,3,4-thiadiazol-2-yl]-3-(4-fluorophenyl)urea.
Chemical Property Profile of 1-{5-[(E)-2-(2-chlorophenyl)ethenyl]-1,3,4-thiadiazol-2-yl}-3-(4-fluorophenyl)urea
Property Insights of 1-{5-[(E)-2-(2-chlorophenyl)ethenyl]-1,3,4-thiadiazol-2-yl}-3-(4-fluorophenyl)urea
The XLogP value of 5.145 indicates that 1-{5-[(E)-2-(2-chlorophenyl)ethenyl]-1,3,4-thiadiazol-2-yl}-3-(4-fluorophenyl)urea is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 66.91 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-{5-[(E)-2-(2-chlorophenyl)ethenyl]-1,3,4-thiadiazol-2-yl}-3-(4-fluorophenyl)urea. Following Lipinski's Rule of Five, 1-{5-[(E)-2-(2-chlorophenyl)ethenyl]-1,3,4-thiadiazol-2-yl}-3-(4-fluorophenyl)urea has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-{5-[(E)-2-(2-chlorophenyl)ethenyl]-1,3,4-thiadiazol-2-yl}-3-(4-fluorophenyl)urea?
The CAS number of 1-{5-[(E)-2-(2-chlorophenyl)ethenyl]-1,3,4-thiadiazol-2-yl}-3-(4-fluorophenyl)urea is 426247-74-7.
What is the molecular formula of 1-{5-[(E)-2-(2-chlorophenyl)ethenyl]-1,3,4-thiadiazol-2-yl}-3-(4-fluorophenyl)urea?
The molecular formula of 1-{5-[(E)-2-(2-chlorophenyl)ethenyl]-1,3,4-thiadiazol-2-yl}-3-(4-fluorophenyl)urea is C17H12ClFN4OS.
What is the molecular weight of 1-{5-[(E)-2-(2-chlorophenyl)ethenyl]-1,3,4-thiadiazol-2-yl}-3-(4-fluorophenyl)urea?
The molecular weight of 1-{5-[(E)-2-(2-chlorophenyl)ethenyl]-1,3,4-thiadiazol-2-yl}-3-(4-fluorophenyl)urea is 374.04 g/mol.
Where can I buy 1-{5-[(E)-2-(2-chlorophenyl)ethenyl]-1,3,4-thiadiazol-2-yl}-3-(4-fluorophenyl)urea?
You can request a quote for 1-{5-[(E)-2-(2-chlorophenyl)ethenyl]-1,3,4-thiadiazol-2-yl}-3-(4-fluorophenyl)urea directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-{5-[(E)-2-(2-chlorophenyl)ethenyl]-1,3,4-thiadiazol-2-yl}-3-(4-fluorophenyl)urea?
Yes, KEHONG BIO provides custom synthesis services for 1-{5-[(E)-2-(2-chlorophenyl)ethenyl]-1,3,4-thiadiazol-2-yl}-3-(4-fluorophenyl)urea and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.