Antibiotic RP 21190 structure

Antibiotic RP 21190

TL;DR: Antibiotic RP 21190 (CAS 42617-24-3) is a chemical compound with molecular formula C61H88Cl2O33 and molecular weight 1418.46 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[(1R,2R,4R,6S)-4-[(2R,2'R,3'S,3aR,4R,4'R,6S,7S,7aR)-6-[(2R,3R,4R,5R,6S)-2-[(2R,3S,4S,5S,6S)-6-[(2R,3aS,3'aR,6S,6'R,7R,7'S,7aR,7'aR)-7'-acetyl-7'-hydroxy-6'-methyl-7-(2-methylpropanoyloxy)spiro[4,6,7,7a-tetrahydro-3aH-[1,3]dioxolo[4,5-c]pyran-2,4'-6,7a-dihydro-3aH-[1,3]dioxolo[4,5-c]pyran]-6-yl]oxy-4-hydroxy-5-methoxy-2-(methoxymethyl)oxan-3-yl]oxy-3,6-dihydroxy-5-methoxyoxan-4-yl]oxy-4',7-dihydroxy-2',4,7a-trimethylspiro[3a,4,6,7-tetrahydro-[1,3]dioxolo[4,5-c]pyran-2,6'-oxane]-3'-yl]oxy-2-hydroxy-6-methylcyclohexyl] 3,5-dichloro-4-hydroxy-2-methoxy-6-methylbenzoate

Also Known As: Flambamycin, Antibiotic RP 21190, [(1R,2R,4R,6S)-4-[(2R,2'R,3'S,3aR,4R,4'R,6S,7S,7aR)-6-[(2R,3R,4R,5R,6S)-2-[(2R,3S,4S,5S,6S)-6-[(2R,3aS,3'aR,6S,6'R,7R,7'S,7aR,7'aR)-7'-acetyl-7'-hydroxy-6'-methyl-7-(2-methylpropanoyloxy)spiro[4,6,7,7a-tetrahydro-3aH-[1,3]dioxolo[4,5-c]pyran-2,4'-6,7a-dihydro-3aH-[1,3]dioxolo[4,5-c]pyran]-6-yl]oxy-4-hydroxy-5-methoxy-2-(methoxymethyl)oxan-3-yl]oxy-3,6-dihydroxy-5-methoxyoxan-4-yl]oxy-4',7-dihydroxy-2',4,7a-trimethylspiro[3a,4,6,7-tetrahydro-[1,3]dioxolo[4,5-c]pyran-2,6'-oxane]-3'-yl]oxy-2-hydroxy-6-methylcyclohexyl] 3,5-dichloro-4-hydroxy-2-methoxy-6-methylbenzoate, (1R,2R,4R,6S)-4-(((2R,3a'R,4R,4'R,5S,6R,6'S,7'S,7a'R)-6'-(((2R,3R,4R,5R,6S)-2-(((2R,3S,4S,5S,6S)-6-(((2R,3aS,3a'R,6S,6'R,7R,7aR,7'S,7a'R)-7'-acetyl-7'-hydroxy-7-(isobutyryloxy)-6'-methyloctahydro-4H-2,4'-spirobi[[1,3]dioxolo[4,5-c]pyran]-6-yl)oxy)-4-hydroxy-5-methoxy-2-(methoxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-3,6-dihydroxy-5-methoxytetrahydro-2H-pyran-4-yl)oxy)-4,7'-dihydroxy-4',6,7a'-trimethyloctahydro-4'H-spiro[pyran-2,2'-[1,3]dioxolo[4,5-c]pyran]-5-yl)oxy)-2-hydroxy-6-methylcyclohexyl 3,5-dichloro-4-hydroxy-2-methoxy-6-methylbenzoate, beta-D-Mannopyranoside, O-4-C-acetyl-6-deoxy-2,3-O-methylenehexopyranosylidene-(1-3-4)-2-O-(2-methyl-1-oxopropyl)-alpha-L-lyxopyranosyl O-2,6-dideoxy-4-O-(3,5-dichloro-4-hydroxy-2-methoxy-6-methylbenzoyl)-beta-D-arabino-hexopyranosyl-(1-4)-O-2,6-dideoxy-D-ribo-hexopyranosylidene-(1-3-4)-O-6-deoxy-3-C-methyl-beta-D-mannopyranosyl-(1-3)-O-6-deoxy-4-O-methyl-beta-D-galactopyranosyl-(1-4)-2,6-di-O-methyl-

CAS: 42617-24-3
Molecular Formula C61H88Cl2O33
Molecular Weight 1418.46 g/mol
LogP -0.38368
Topological Polar Surface Area 416.11 Ų
Hydrogen Bond Donors 8
Hydrogen Bond Acceptors 33
Rotatable Bonds 18
Exact Mass 1418.4585
Heavy Atoms 96
Complexity 2926.8452

Chemical Identifiers

CAS Number 42617-24-3
SMILES C[C@H]1C[C@H](C[C@H]([C@@H]1OC(=O)C2=C(C(=C(C(=C2OC)Cl)O)Cl)C)O)O[C@@H]3[C@H](O[C@]4(C[C@H]3O)O[C@@H]5[C@H](O[C@H]([C@H]([C@]5(O4)C)O)O[C@@H]6[C@H]([C@@H](O[C@@H]([C@@H]6OC)O)O[C@@H]7[C@H](O[C@H]([C@H]([C@H]7O)OC)O[C@H]8[C@@H]([C@H]9[C@H](CO8)O[C@@]1(O9)[C@H]2[C@H]([C@@]([C@H](O1)C)(C(=O)C)O)OCO2)OC(=O)C(C)C)COC)O)C)C

Product Overview

Antibiotic RP 21190 (CAS 42617-24-3), with molecular formula C61H88Cl2O33 and molecular weight 1418.46 g/mol. IUPAC: [(1R,2R,4R,6S)-4-[(2R,2'R,3'S,3aR,4R,4'R,6S,7S,7aR)-6-[(2R,3R,4R,5R,6S)-2-[(2R,3S,4S,5S,6S)-6-[(2R,3aS,3'aR,6S,6'R,7R,7'S,7aR,7'aR)-7'-acetyl-7'-hydroxy-6'-methyl-7-(2-methylpropanoyloxy)spiro[4,6,7,7a-tetrahydro-3aH-[1,3]dioxolo[4,5-c]pyran-2,4'-6,7a-dihydro-3aH-[1,3]dioxolo[4,5-c]pyran]-6-yl]oxy-4-hydroxy-5-methoxy-2-(methoxymethyl)oxan-3-yl]oxy-3,6-dihydroxy-5-methoxyoxan-4-yl]oxy-4',7-dihydroxy-2',4,7a-trimethylspiro[3a,4,6,7-tetrahydro-[1,3]dioxolo[4,5-c]pyran-2,6'-oxane]-3'-yl]oxy-2-hydroxy-6-methylcyclohexyl] 3,5-dichloro-4-hydroxy-2-methoxy-6-methylbenzoate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Antibiotic RP 21190

XLogP
-0.38368
TPSA (Topological Polar Surface Area)
416.11
Hydrogen Bond Donors
8
Hydrogen Bond Acceptors
33
Rotatable Bonds
18
Heavy Atoms
96
Complexity
2926.8452
Exact Mass
1418.4585
Monoisotopic Mass
1418.4585
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Antibiotic RP 21190

The XLogP value of -0.38368 indicates that Antibiotic RP 21190 is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 416.11 Ų indicates high polarity, suggesting Antibiotic RP 21190 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Antibiotic RP 21190 has 8 hydrogen bond donor(s) and 33 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Antibiotic RP 21190?

The CAS number of Antibiotic RP 21190 is 42617-24-3.

What is the molecular formula of Antibiotic RP 21190?

The molecular formula of Antibiotic RP 21190 is C61H88Cl2O33.

What is the molecular weight of Antibiotic RP 21190?

The molecular weight of Antibiotic RP 21190 is 1418.46 g/mol.

Where can I buy Antibiotic RP 21190?

You can request a quote for Antibiotic RP 21190 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Antibiotic RP 21190?

Yes, KEHONG BIO provides custom synthesis services for Antibiotic RP 21190 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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