Histidyl-proline diketopiperazine
TL;DR: Histidyl-proline diketopiperazine (CAS 4257-92-5) is a chemical compound with molecular formula C12H16N4O2 and molecular weight 248.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(3S,9aS)-3-(1H-imidazol-5-ylmethyl)-3,6,7,8,9,9a-hexahydro-2H-pyrido[1,2-a]pyrazine-1,4-dione
Also Known As: His-pro-dkp, Cyclo(his-pro), Cyclo(histidyl-prolyl), Histidylproline diketopiperazine, Cyclo(-His-Pro)
| Molecular Formula | C12H16N4O2 |
|---|---|
| Molecular Weight | 248.13 g/mol |
| LogP | -0.1 |
| Topological Polar Surface Area | 78.1 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 248.12732 |
| Heavy Atoms | 18 |
| Complexity | 360.0 |
Chemical Identifiers
| CAS Number | 4257-92-5 |
|---|---|
| SMILES | C1CCN2[C@@H](C1)C(=O)N[C@H](C2=O)CC3=CN=CN3 |
| InChIKey | LCXWQHWWTPOAFI-UWVGGRQHSA-N |
Product Overview
Histidyl-proline diketopiperazine (CAS 4257-92-5), with molecular formula C12H16N4O2 and molecular weight 248.13 g/mol. IUPAC: (3S,9aS)-3-(1H-imidazol-5-ylmethyl)-3,6,7,8,9,9a-hexahydro-2H-pyrido[1,2-a]pyrazine-1,4-dione.
Chemical Property Profile of Histidyl-proline diketopiperazine
Property Insights of Histidyl-proline diketopiperazine
The XLogP value of -0.1 indicates that Histidyl-proline diketopiperazine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 78.1 Ų falls within the moderate polarity range, balancing permeability and solubility for Histidyl-proline diketopiperazine. Following Lipinski's Rule of Five, Histidyl-proline diketopiperazine has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Histidyl-proline diketopiperazine?
The CAS number of Histidyl-proline diketopiperazine is 4257-92-5.
What is the molecular formula of Histidyl-proline diketopiperazine?
The molecular formula of Histidyl-proline diketopiperazine is C12H16N4O2.
What is the molecular weight of Histidyl-proline diketopiperazine?
The molecular weight of Histidyl-proline diketopiperazine is 248.13 g/mol.
Where can I buy Histidyl-proline diketopiperazine?
You can request a quote for Histidyl-proline diketopiperazine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Histidyl-proline diketopiperazine?
Yes, KEHONG BIO provides custom synthesis services for Histidyl-proline diketopiperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.