5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1H-pyrrol-2(5H)-one
TL;DR: 5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1H-pyrrol-2(5H)-one (CAS 425617-22-7) is a chemical compound with molecular formula C24H17F2NO3 and molecular weight 405.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4E)-5-(3-fluorophenyl)-1-(4-fluorophenyl)-4-[hydroxy-(4-methylphenyl)methylidene]pyrrolidine-2,3-dione
Also Known As: 5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1H-pyrrol-2(5H)-one, (4E)-5-(3-fluorophenyl)-1-(4-fluorophenyl)-4-[hydroxy(4-methylphenyl)methylidene]pyrrolidine-2,3-dione, (4E)-5-(3-fluorophenyl)-1-(4-fluorophenyl)-4-[hydroxy-(4-methylphenyl)methylidene]pyrrolidine-2,3-dione, 5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1,5-dihydro-2H-pyrrol-2-one
| Molecular Formula | C24H17F2NO3 |
|---|---|
| Molecular Weight | 405.12 g/mol |
| LogP | 4.89952 |
| Topological Polar Surface Area | 57.61 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 405.11765 |
| Heavy Atoms | 30 |
| Complexity | 1167.8153 |
Chemical Identifiers
| CAS Number | 425617-22-7 |
|---|---|
| SMILES | CC1=CC=C(C=C1)/C(=C\2/C(N(C(=O)C2=O)C3=CC=C(C=C3)F)C4=CC(=CC=C4)F)/O |
Product Overview
5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1H-pyrrol-2(5H)-one (CAS 425617-22-7), with molecular formula C24H17F2NO3 and molecular weight 405.12 g/mol. IUPAC: (4E)-5-(3-fluorophenyl)-1-(4-fluorophenyl)-4-[hydroxy-(4-methylphenyl)methylidene]pyrrolidine-2,3-dione.
Chemical Property Profile of 5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1H-pyrrol-2(5H)-one
Property Insights of 5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1H-pyrrol-2(5H)-one
The XLogP value of 4.89952 indicates that 5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1H-pyrrol-2(5H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 57.61 Ų, 5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1H-pyrrol-2(5H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1H-pyrrol-2(5H)-one has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1H-pyrrol-2(5H)-one?
The CAS number of 5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1H-pyrrol-2(5H)-one is 425617-22-7.
What is the molecular formula of 5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1H-pyrrol-2(5H)-one?
The molecular formula of 5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1H-pyrrol-2(5H)-one is C24H17F2NO3.
What is the molecular weight of 5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1H-pyrrol-2(5H)-one?
The molecular weight of 5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1H-pyrrol-2(5H)-one is 405.12 g/mol.
Where can I buy 5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1H-pyrrol-2(5H)-one?
You can request a quote for 5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1H-pyrrol-2(5H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1H-pyrrol-2(5H)-one?
Yes, KEHONG BIO provides custom synthesis services for 5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1H-pyrrol-2(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.