3-acetyl-2-(4-bromophenyl)-4-hydroxy-1-(1,3-thiazol-2-yl)-2H-pyrrol-5-one
TL;DR: 3-acetyl-2-(4-bromophenyl)-4-hydroxy-1-(1,3-thiazol-2-yl)-2H-pyrrol-5-one (CAS 425614-52-4) is a chemical compound with molecular formula C15H11BrN2O3S and molecular weight 377.97 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-acetyl-2-(4-bromophenyl)-4-hydroxy-1-(1,3-thiazol-2-yl)-2H-pyrrol-5-one
Also Known As: 3-acetyl-2-(4-bromophenyl)-4-hydroxy-1-(1,3-thiazol-2-yl)-2H-pyrrol-5-one, 4-acetyl-5-(4-bromophenyl)-3-hydroxy-1-(1,3-thiazol-2-yl)-1,5-dihydro-2H-pyrrol-2-one, 4-acetyl-5-(4-bromophenyl)-3-hydroxy-1-(thiazol-2-yl)-1H-pyrrol-2(5H)-one
| Molecular Formula | C15H11BrN2O3S |
|---|---|
| Molecular Weight | 377.97 g/mol |
| LogP | 3.3946 |
| Topological Polar Surface Area | 70.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 377.96738 |
| Heavy Atoms | 22 |
| Complexity | 768.5951 |
Chemical Identifiers
| CAS Number | 425614-52-4 |
|---|---|
| SMILES | CC(=O)C1=C(C(=O)N(C1C2=CC=C(C=C2)Br)C3=NC=CS3)O |
Product Overview
3-acetyl-2-(4-bromophenyl)-4-hydroxy-1-(1,3-thiazol-2-yl)-2H-pyrrol-5-one (CAS 425614-52-4), with molecular formula C15H11BrN2O3S and molecular weight 377.97 g/mol. IUPAC: 3-acetyl-2-(4-bromophenyl)-4-hydroxy-1-(1,3-thiazol-2-yl)-2H-pyrrol-5-one.
Chemical Property Profile of 3-acetyl-2-(4-bromophenyl)-4-hydroxy-1-(1,3-thiazol-2-yl)-2H-pyrrol-5-one
Property Insights of 3-acetyl-2-(4-bromophenyl)-4-hydroxy-1-(1,3-thiazol-2-yl)-2H-pyrrol-5-one
The XLogP value of 3.3946 indicates that 3-acetyl-2-(4-bromophenyl)-4-hydroxy-1-(1,3-thiazol-2-yl)-2H-pyrrol-5-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 70.5 Ų falls within the moderate polarity range, balancing permeability and solubility for 3-acetyl-2-(4-bromophenyl)-4-hydroxy-1-(1,3-thiazol-2-yl)-2H-pyrrol-5-one. Following Lipinski's Rule of Five, 3-acetyl-2-(4-bromophenyl)-4-hydroxy-1-(1,3-thiazol-2-yl)-2H-pyrrol-5-one has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-acetyl-2-(4-bromophenyl)-4-hydroxy-1-(1,3-thiazol-2-yl)-2H-pyrrol-5-one?
The CAS number of 3-acetyl-2-(4-bromophenyl)-4-hydroxy-1-(1,3-thiazol-2-yl)-2H-pyrrol-5-one is 425614-52-4.
What is the molecular formula of 3-acetyl-2-(4-bromophenyl)-4-hydroxy-1-(1,3-thiazol-2-yl)-2H-pyrrol-5-one?
The molecular formula of 3-acetyl-2-(4-bromophenyl)-4-hydroxy-1-(1,3-thiazol-2-yl)-2H-pyrrol-5-one is C15H11BrN2O3S.
What is the molecular weight of 3-acetyl-2-(4-bromophenyl)-4-hydroxy-1-(1,3-thiazol-2-yl)-2H-pyrrol-5-one?
The molecular weight of 3-acetyl-2-(4-bromophenyl)-4-hydroxy-1-(1,3-thiazol-2-yl)-2H-pyrrol-5-one is 377.97 g/mol.
Where can I buy 3-acetyl-2-(4-bromophenyl)-4-hydroxy-1-(1,3-thiazol-2-yl)-2H-pyrrol-5-one?
You can request a quote for 3-acetyl-2-(4-bromophenyl)-4-hydroxy-1-(1,3-thiazol-2-yl)-2H-pyrrol-5-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-acetyl-2-(4-bromophenyl)-4-hydroxy-1-(1,3-thiazol-2-yl)-2H-pyrrol-5-one?
Yes, KEHONG BIO provides custom synthesis services for 3-acetyl-2-(4-bromophenyl)-4-hydroxy-1-(1,3-thiazol-2-yl)-2H-pyrrol-5-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.