1-benzyl-4-(4-chlorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1,5-dihydro-2H-pyrrol-2-one
TL;DR: 1-benzyl-4-(4-chlorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1,5-dihydro-2H-pyrrol-2-one (CAS 425614-25-1) is a chemical compound with molecular formula C24H17ClFNO3 and molecular weight 421.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4E)-1-benzyl-4-[(4-chlorophenyl)-hydroxymethylidene]-5-(2-fluorophenyl)pyrrolidine-2,3-dione
Also Known As: 1-benzyl-4-(4-chlorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1,5-dihydro-2H-pyrrol-2-one, 1-benzyl-4-[(4-chlorophenyl)-hydroxy-methylidene]-5-(2-fluorophenyl)pyrrolidine-2,3-dione, (4E)-1-benzyl-4-[(4-chlorophenyl)(hydroxy)methylidene]-5-(2-fluorophenyl)pyrrolidine-2,3-dione, (4E)-1-benzyl-4-[(4-chlorophenyl)-hydroxymethylidene]-5-(2-fluorophenyl)pyrrolidine-2,3-dione
| Molecular Formula | C24H17ClFNO3 |
|---|---|
| Molecular Weight | 421.09 g/mol |
| LogP | 5.101 |
| Topological Polar Surface Area | 57.61 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 421.0881 |
| Heavy Atoms | 30 |
| Complexity | 1142.6273 |
Chemical Identifiers
| CAS Number | 425614-25-1 |
|---|---|
| SMILES | C1=CC=C(C=C1)CN2C(/C(=C(/C3=CC=C(C=C3)Cl)\O)/C(=O)C2=O)C4=CC=CC=C4F |
Product Overview
1-benzyl-4-(4-chlorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1,5-dihydro-2H-pyrrol-2-one (CAS 425614-25-1), with molecular formula C24H17ClFNO3 and molecular weight 421.09 g/mol. IUPAC: (4E)-1-benzyl-4-[(4-chlorophenyl)-hydroxymethylidene]-5-(2-fluorophenyl)pyrrolidine-2,3-dione.
Chemical Property Profile of 1-benzyl-4-(4-chlorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1,5-dihydro-2H-pyrrol-2-one
Property Insights of 1-benzyl-4-(4-chlorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1,5-dihydro-2H-pyrrol-2-one
The XLogP value of 5.101 indicates that 1-benzyl-4-(4-chlorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1,5-dihydro-2H-pyrrol-2-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 57.61 Ų, 1-benzyl-4-(4-chlorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1,5-dihydro-2H-pyrrol-2-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-benzyl-4-(4-chlorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1,5-dihydro-2H-pyrrol-2-one has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-benzyl-4-(4-chlorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1,5-dihydro-2H-pyrrol-2-one?
The CAS number of 1-benzyl-4-(4-chlorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1,5-dihydro-2H-pyrrol-2-one is 425614-25-1.
What is the molecular formula of 1-benzyl-4-(4-chlorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1,5-dihydro-2H-pyrrol-2-one?
The molecular formula of 1-benzyl-4-(4-chlorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1,5-dihydro-2H-pyrrol-2-one is C24H17ClFNO3.
What is the molecular weight of 1-benzyl-4-(4-chlorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1,5-dihydro-2H-pyrrol-2-one?
The molecular weight of 1-benzyl-4-(4-chlorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1,5-dihydro-2H-pyrrol-2-one is 421.09 g/mol.
Where can I buy 1-benzyl-4-(4-chlorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1,5-dihydro-2H-pyrrol-2-one?
You can request a quote for 1-benzyl-4-(4-chlorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1,5-dihydro-2H-pyrrol-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-benzyl-4-(4-chlorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1,5-dihydro-2H-pyrrol-2-one?
Yes, KEHONG BIO provides custom synthesis services for 1-benzyl-4-(4-chlorobenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1,5-dihydro-2H-pyrrol-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.