3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1-(2-phenylethyl)-1,5-dihydro-2H-pyrrol-2-one
TL;DR: 3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1-(2-phenylethyl)-1,5-dihydro-2H-pyrrol-2-one (CAS 425424-40-4) is a chemical compound with molecular formula C26H23NO3 and molecular weight 397.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4E)-4-[hydroxy-(4-methylphenyl)methylidene]-5-phenyl-1-(2-phenylethyl)pyrrolidine-2,3-dione
Also Known As: 3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1-(2-phenylethyl)-1,5-dihydro-2H-pyrrol-2-one, 3-hydroxy-4-(4-methylbenzoyl)-1-phenethyl-5-phenyl-1H-pyrrol-2(5H)-one, 3-hydroxy-4-[(4-methylphenyl)carbonyl]-5-phenyl-1-(2-phenylethyl)-1,5-dihydro-2H-pyrrol-2-one, (4E)-4-[hydroxy-(4-methylphenyl)methylidene]-1-phenethyl-5-phenylpyrrolidine-2,3-dione
| Molecular Formula | C26H23NO3 |
|---|---|
| Molecular Weight | 397.17 g/mol |
| LogP | 4.65942 |
| Topological Polar Surface Area | 57.61 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 397.1678 |
| Heavy Atoms | 30 |
| Complexity | 1086.1422 |
Chemical Identifiers
| CAS Number | 425424-40-4 |
|---|---|
| SMILES | CC1=CC=C(C=C1)/C(=C\2/C(N(C(=O)C2=O)CCC3=CC=CC=C3)C4=CC=CC=C4)/O |
Product Overview
3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1-(2-phenylethyl)-1,5-dihydro-2H-pyrrol-2-one (CAS 425424-40-4), with molecular formula C26H23NO3 and molecular weight 397.17 g/mol. IUPAC: (4E)-4-[hydroxy-(4-methylphenyl)methylidene]-5-phenyl-1-(2-phenylethyl)pyrrolidine-2,3-dione.
Chemical Property Profile of 3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1-(2-phenylethyl)-1,5-dihydro-2H-pyrrol-2-one
Property Insights of 3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1-(2-phenylethyl)-1,5-dihydro-2H-pyrrol-2-one
The XLogP value of 4.65942 indicates that 3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1-(2-phenylethyl)-1,5-dihydro-2H-pyrrol-2-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 57.61 Ų, 3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1-(2-phenylethyl)-1,5-dihydro-2H-pyrrol-2-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1-(2-phenylethyl)-1,5-dihydro-2H-pyrrol-2-one has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1-(2-phenylethyl)-1,5-dihydro-2H-pyrrol-2-one?
The CAS number of 3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1-(2-phenylethyl)-1,5-dihydro-2H-pyrrol-2-one is 425424-40-4.
What is the molecular formula of 3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1-(2-phenylethyl)-1,5-dihydro-2H-pyrrol-2-one?
The molecular formula of 3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1-(2-phenylethyl)-1,5-dihydro-2H-pyrrol-2-one is C26H23NO3.
What is the molecular weight of 3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1-(2-phenylethyl)-1,5-dihydro-2H-pyrrol-2-one?
The molecular weight of 3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1-(2-phenylethyl)-1,5-dihydro-2H-pyrrol-2-one is 397.17 g/mol.
Where can I buy 3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1-(2-phenylethyl)-1,5-dihydro-2H-pyrrol-2-one?
You can request a quote for 3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1-(2-phenylethyl)-1,5-dihydro-2H-pyrrol-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1-(2-phenylethyl)-1,5-dihydro-2H-pyrrol-2-one?
Yes, KEHONG BIO provides custom synthesis services for 3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1-(2-phenylethyl)-1,5-dihydro-2H-pyrrol-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.