4-(4-chlorobenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(4-methoxyphenyl)-1H-pyrrol-2(5H)-one
TL;DR: 4-(4-chlorobenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(4-methoxyphenyl)-1H-pyrrol-2(5H)-one (CAS 425413-18-9) is a chemical compound with molecular formula C24H17ClFNO4 and molecular weight 437.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4E)-4-[(4-chlorophenyl)-hydroxymethylidene]-5-(4-fluorophenyl)-1-(4-methoxyphenyl)pyrrolidine-2,3-dione
Also Known As: 4-(4-chlorobenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(4-methoxyphenyl)-1H-pyrrol-2(5H)-one, (4E)-4-[(4-chlorophenyl)-hydroxymethylidene]-5-(4-fluorophenyl)-1-(4-methoxyphenyl)pyrrolidine-2,3-dione
| Molecular Formula | C24H17ClFNO4 |
|---|---|
| Molecular Weight | 437.08 g/mol |
| LogP | 5.114 |
| Topological Polar Surface Area | 66.84 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 437.083 |
| Heavy Atoms | 31 |
| Complexity | 1171.7109 |
Chemical Identifiers
| CAS Number | 425413-18-9 |
|---|---|
| SMILES | COC1=CC=C(C=C1)N2C(/C(=C(/C3=CC=C(C=C3)Cl)\O)/C(=O)C2=O)C4=CC=C(C=C4)F |
Product Overview
4-(4-chlorobenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(4-methoxyphenyl)-1H-pyrrol-2(5H)-one (CAS 425413-18-9), with molecular formula C24H17ClFNO4 and molecular weight 437.08 g/mol. IUPAC: (4E)-4-[(4-chlorophenyl)-hydroxymethylidene]-5-(4-fluorophenyl)-1-(4-methoxyphenyl)pyrrolidine-2,3-dione.
Chemical Property Profile of 4-(4-chlorobenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(4-methoxyphenyl)-1H-pyrrol-2(5H)-one
Property Insights of 4-(4-chlorobenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(4-methoxyphenyl)-1H-pyrrol-2(5H)-one
The XLogP value of 5.114 indicates that 4-(4-chlorobenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(4-methoxyphenyl)-1H-pyrrol-2(5H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 66.84 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-(4-chlorobenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(4-methoxyphenyl)-1H-pyrrol-2(5H)-one. Following Lipinski's Rule of Five, 4-(4-chlorobenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(4-methoxyphenyl)-1H-pyrrol-2(5H)-one has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(4-chlorobenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(4-methoxyphenyl)-1H-pyrrol-2(5H)-one?
The CAS number of 4-(4-chlorobenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(4-methoxyphenyl)-1H-pyrrol-2(5H)-one is 425413-18-9.
What is the molecular formula of 4-(4-chlorobenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(4-methoxyphenyl)-1H-pyrrol-2(5H)-one?
The molecular formula of 4-(4-chlorobenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(4-methoxyphenyl)-1H-pyrrol-2(5H)-one is C24H17ClFNO4.
What is the molecular weight of 4-(4-chlorobenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(4-methoxyphenyl)-1H-pyrrol-2(5H)-one?
The molecular weight of 4-(4-chlorobenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(4-methoxyphenyl)-1H-pyrrol-2(5H)-one is 437.08 g/mol.
Where can I buy 4-(4-chlorobenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(4-methoxyphenyl)-1H-pyrrol-2(5H)-one?
You can request a quote for 4-(4-chlorobenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(4-methoxyphenyl)-1H-pyrrol-2(5H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(4-chlorobenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(4-methoxyphenyl)-1H-pyrrol-2(5H)-one?
Yes, KEHONG BIO provides custom synthesis services for 4-(4-chlorobenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(4-methoxyphenyl)-1H-pyrrol-2(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.