![Thiophen-2-yl{4-[2-(trifluoromethyl)benzyl]piperazin-1-yl}methanone structure](/static/products/4253/425395-50-2.webp)
Thiophen-2-yl{4-[2-(trifluoromethyl)benzyl]piperazin-1-yl}methanone
TL;DR: Thiophen-2-yl{4-[2-(trifluoromethyl)benzyl]piperazin-1-yl}methanone (CAS 425395-50-2) is a chemical compound with molecular formula C17H17F3N2OS and molecular weight 354.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
thiophen-2-yl-[4-[[2-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]methanone
Also Known As: Thiophen-2-yl-[4-[[2-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]methanone, 2-THIENYL{4-[2-(TRIFLUOROMETHYL)BENZYL]PIPERAZINO}METHANONE, thiophen-2-yl{4-[2-(trifluoromethyl)benzyl]piperazin-1-yl}methanone, 1-(THIOPHENE-2-CARBONYL)-4-{[2-(TRIFLUOROMETHYL)PHENYL]METHYL}PIPERAZINE
| Molecular Formula | C17H17F3N2OS |
|---|---|
| Molecular Weight | 354.10 g/mol |
| LogP | 3.7249 |
| Topological Polar Surface Area | 23.55 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 354.10138 |
| Heavy Atoms | 24 |
| Complexity | 692.11127 |
Chemical Identifiers
| CAS Number | 425395-50-2 |
|---|---|
| SMILES | C1CN(CCN1CC2=CC=CC=C2C(F)(F)F)C(=O)C3=CC=CS3 |
Product Overview
Thiophen-2-yl{4-[2-(trifluoromethyl)benzyl]piperazin-1-yl}methanone (CAS 425395-50-2), with molecular formula C17H17F3N2OS and molecular weight 354.10 g/mol. IUPAC: thiophen-2-yl-[4-[[2-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]methanone.
Chemical Property Profile of Thiophen-2-yl{4-[2-(trifluoromethyl)benzyl]piperazin-1-yl}methanone
Property Insights of Thiophen-2-yl{4-[2-(trifluoromethyl)benzyl]piperazin-1-yl}methanone
The XLogP value of 3.7249 indicates that Thiophen-2-yl{4-[2-(trifluoromethyl)benzyl]piperazin-1-yl}methanone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 23.55 Ų, Thiophen-2-yl{4-[2-(trifluoromethyl)benzyl]piperazin-1-yl}methanone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Thiophen-2-yl{4-[2-(trifluoromethyl)benzyl]piperazin-1-yl}methanone has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Thiophen-2-yl{4-[2-(trifluoromethyl)benzyl]piperazin-1-yl}methanone?
The CAS number of Thiophen-2-yl{4-[2-(trifluoromethyl)benzyl]piperazin-1-yl}methanone is 425395-50-2.
What is the molecular formula of Thiophen-2-yl{4-[2-(trifluoromethyl)benzyl]piperazin-1-yl}methanone?
The molecular formula of Thiophen-2-yl{4-[2-(trifluoromethyl)benzyl]piperazin-1-yl}methanone is C17H17F3N2OS.
What is the molecular weight of Thiophen-2-yl{4-[2-(trifluoromethyl)benzyl]piperazin-1-yl}methanone?
The molecular weight of Thiophen-2-yl{4-[2-(trifluoromethyl)benzyl]piperazin-1-yl}methanone is 354.10 g/mol.
Where can I buy Thiophen-2-yl{4-[2-(trifluoromethyl)benzyl]piperazin-1-yl}methanone?
You can request a quote for Thiophen-2-yl{4-[2-(trifluoromethyl)benzyl]piperazin-1-yl}methanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Thiophen-2-yl{4-[2-(trifluoromethyl)benzyl]piperazin-1-yl}methanone?
Yes, KEHONG BIO provides custom synthesis services for Thiophen-2-yl{4-[2-(trifluoromethyl)benzyl]piperazin-1-yl}methanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.