Tpa-023B
TL;DR: Tpa-023B (CAS 425377-76-0) is a chemical compound with molecular formula C21H15F2N5O and molecular weight 391.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-fluoro-2-[2-fluoro-5-[3-(2-hydroxypropan-2-yl)imidazo[1,2-b][1,2,4]triazin-7-yl]phenyl]benzonitrile
Also Known As: TPA-023B, 1,4-Benzenedipropanamine, TPA 023B, TPA023B, CAS-NOCAS_47330
| Molecular Formula | C21H15F2N5O |
|---|---|
| Molecular Weight | 391.12 g/mol |
| LogP | 3.83558 |
| Topological Polar Surface Area | 87.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 391.12448 |
| Heavy Atoms | 29 |
| Complexity | 1284.7017 |
Chemical Identifiers
| CAS Number | 425377-76-0 |
|---|---|
| SMILES | CC(C)(C1=NC2=NC=C(N2N=C1)C3=CC(=C(C=C3)F)C4=C(C=CC=C4F)C#N)O |
Product Overview
Tpa-023B (CAS 425377-76-0), with molecular formula C21H15F2N5O and molecular weight 391.12 g/mol. IUPAC: 3-fluoro-2-[2-fluoro-5-[3-(2-hydroxypropan-2-yl)imidazo[1,2-b][1,2,4]triazin-7-yl]phenyl]benzonitrile.
Chemical Property Profile of Tpa-023B
Property Insights of Tpa-023B
The XLogP value of 3.83558 indicates that Tpa-023B is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 87.1 Ų falls within the moderate polarity range, balancing permeability and solubility for Tpa-023B. Following Lipinski's Rule of Five, Tpa-023B has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Tpa-023B?
The CAS number of Tpa-023B is 425377-76-0.
What is the molecular formula of Tpa-023B?
The molecular formula of Tpa-023B is C21H15F2N5O.
What is the molecular weight of Tpa-023B?
The molecular weight of Tpa-023B is 391.12 g/mol.
Where can I buy Tpa-023B?
You can request a quote for Tpa-023B directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Tpa-023B?
Yes, KEHONG BIO provides custom synthesis services for Tpa-023B and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.