N-(1,1-Dimethyl-2-phenylethyl)-2,2,2-trifluoroacetamide
TL;DR: N-(1,1-Dimethyl-2-phenylethyl)-2,2,2-trifluoroacetamide (CAS 42524-63-0) is a chemical compound with molecular formula C12H14F3NO and molecular weight 245.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2,2,2-trifluoro-N-(2-methyl-1-phenylpropan-2-yl)acetamide
Also Known As: N-Trifluoroacetyl-phentermine, N-(1,1-Dimethyl-2-phenylethyl)-2,2,2-trifluoroacetamide, 2,2,2-trifluoro-N-(2-methyl-1-phenylpropan-2-yl)acetamide, 2,2,2-trifluoro-N-(2-phenyl-1,1-dimethylethyl)acetamide, N-(1,1-dimethyl-2-phenyl-ethyl)-2,2,2-trifluoroacetamide
| Molecular Formula | C12H14F3NO |
|---|---|
| Molecular Weight | 245.10 g/mol |
| LogP | 3.2 |
| Topological Polar Surface Area | 29.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 245.10275 |
| Heavy Atoms | 17 |
| Complexity | 267.0 |
Chemical Identifiers
| CAS Number | 42524-63-0 |
|---|---|
| SMILES | CC(C)(CC1=CC=CC=C1)NC(=O)C(F)(F)F |
| InChIKey | PRARTRNWRNYCID-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
N-(1,1-Dimethyl-2-phenylethyl)-2,2,2-trifluoroacetamide (CAS 42524-63-0), with molecular formula C12H14F3NO and molecular weight 245.10 g/mol. IUPAC: 2,2,2-trifluoro-N-(2-methyl-1-phenylpropan-2-yl)acetamide.
Chemical Property Profile of N-(1,1-Dimethyl-2-phenylethyl)-2,2,2-trifluoroacetamide
Property Insights of N-(1,1-Dimethyl-2-phenylethyl)-2,2,2-trifluoroacetamide
The XLogP value of 3.2 indicates that N-(1,1-Dimethyl-2-phenylethyl)-2,2,2-trifluoroacetamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 29.1 Ų, N-(1,1-Dimethyl-2-phenylethyl)-2,2,2-trifluoroacetamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(1,1-Dimethyl-2-phenylethyl)-2,2,2-trifluoroacetamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(1,1-Dimethyl-2-phenylethyl)-2,2,2-trifluoroacetamide?
The CAS number of N-(1,1-Dimethyl-2-phenylethyl)-2,2,2-trifluoroacetamide is 42524-63-0.
What is the molecular formula of N-(1,1-Dimethyl-2-phenylethyl)-2,2,2-trifluoroacetamide?
The molecular formula of N-(1,1-Dimethyl-2-phenylethyl)-2,2,2-trifluoroacetamide is C12H14F3NO.
What is the molecular weight of N-(1,1-Dimethyl-2-phenylethyl)-2,2,2-trifluoroacetamide?
The molecular weight of N-(1,1-Dimethyl-2-phenylethyl)-2,2,2-trifluoroacetamide is 245.10 g/mol.
Where can I buy N-(1,1-Dimethyl-2-phenylethyl)-2,2,2-trifluoroacetamide?
You can request a quote for N-(1,1-Dimethyl-2-phenylethyl)-2,2,2-trifluoroacetamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(1,1-Dimethyl-2-phenylethyl)-2,2,2-trifluoroacetamide?
Yes, KEHONG BIO provides custom synthesis services for N-(1,1-Dimethyl-2-phenylethyl)-2,2,2-trifluoroacetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.