![N-[4-(trifluoromethoxy)phenyl]nicotinamide structure](/static/products/4248/424801-67-2.webp)
N-[4-(trifluoromethoxy)phenyl]nicotinamide
TL;DR: N-[4-(trifluoromethoxy)phenyl]nicotinamide (CAS 424801-67-2) is a chemical compound with molecular formula C13H9F3N2O2 and molecular weight 282.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide
Also Known As: N-[4-(trifluoromethoxy)phenyl]nicotinamide, BIM-0045846.P001, N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide, AO-854/12910534
| Molecular Formula | C13H9F3N2O2 |
|---|---|
| Molecular Weight | 282.06 g/mol |
| LogP | 3.2325 |
| Topological Polar Surface Area | 51.22 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 282.0616 |
| Heavy Atoms | 20 |
| Complexity | 582.8153 |
Chemical Identifiers
| CAS Number | 424801-67-2 |
|---|---|
| SMILES | C1=CC(=CN=C1)C(=O)NC2=CC=C(C=C2)OC(F)(F)F |
Product Overview
N-[4-(trifluoromethoxy)phenyl]nicotinamide (CAS 424801-67-2), with molecular formula C13H9F3N2O2 and molecular weight 282.06 g/mol. IUPAC: N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide.
Chemical Property Profile of N-[4-(trifluoromethoxy)phenyl]nicotinamide
Property Insights of N-[4-(trifluoromethoxy)phenyl]nicotinamide
The XLogP value of 3.2325 indicates that N-[4-(trifluoromethoxy)phenyl]nicotinamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 51.22 Ų, N-[4-(trifluoromethoxy)phenyl]nicotinamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-[4-(trifluoromethoxy)phenyl]nicotinamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-[4-(trifluoromethoxy)phenyl]nicotinamide?
The CAS number of N-[4-(trifluoromethoxy)phenyl]nicotinamide is 424801-67-2.
What is the molecular formula of N-[4-(trifluoromethoxy)phenyl]nicotinamide?
The molecular formula of N-[4-(trifluoromethoxy)phenyl]nicotinamide is C13H9F3N2O2.
What is the molecular weight of N-[4-(trifluoromethoxy)phenyl]nicotinamide?
The molecular weight of N-[4-(trifluoromethoxy)phenyl]nicotinamide is 282.06 g/mol.
Where can I buy N-[4-(trifluoromethoxy)phenyl]nicotinamide?
You can request a quote for N-[4-(trifluoromethoxy)phenyl]nicotinamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-[4-(trifluoromethoxy)phenyl]nicotinamide?
Yes, KEHONG BIO provides custom synthesis services for N-[4-(trifluoromethoxy)phenyl]nicotinamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.