1-(4-Chlorobenzyl)-4-(2-thienylcarbonyl)piperazine
TL;DR: 1-(4-Chlorobenzyl)-4-(2-thienylcarbonyl)piperazine (CAS 423744-78-9) is a chemical compound with molecular formula C16H17ClN2OS and molecular weight 320.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[4-[(4-chlorophenyl)methyl]piperazin-1-yl]-thiophen-2-ylmethanone
Also Known As: BAS 02500465, BIM-0038372.P001, 1-(4-chlorobenzyl)-4-(2-thienylcarbonyl)piperazine, AT-057/15364372, [4-[(4-chlorophenyl)methyl]piperazin-1-yl]-thiophen-2-ylmethanone
| Molecular Formula | C16H17ClN2OS |
|---|---|
| Molecular Weight | 320.07 g/mol |
| LogP | 3.3595 |
| Topological Polar Surface Area | 23.55 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 320.075 |
| Heavy Atoms | 21 |
| Complexity | 589.2493 |
Chemical Identifiers
| CAS Number | 423744-78-9 |
|---|---|
| SMILES | C1CN(CCN1CC2=CC=C(C=C2)Cl)C(=O)C3=CC=CS3 |
Product Overview
1-(4-Chlorobenzyl)-4-(2-thienylcarbonyl)piperazine (CAS 423744-78-9), with molecular formula C16H17ClN2OS and molecular weight 320.07 g/mol. IUPAC: [4-[(4-chlorophenyl)methyl]piperazin-1-yl]-thiophen-2-ylmethanone.
Chemical Property Profile of 1-(4-Chlorobenzyl)-4-(2-thienylcarbonyl)piperazine
Property Insights of 1-(4-Chlorobenzyl)-4-(2-thienylcarbonyl)piperazine
The XLogP value of 3.3595 indicates that 1-(4-Chlorobenzyl)-4-(2-thienylcarbonyl)piperazine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 23.55 Ų, 1-(4-Chlorobenzyl)-4-(2-thienylcarbonyl)piperazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(4-Chlorobenzyl)-4-(2-thienylcarbonyl)piperazine has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(4-Chlorobenzyl)-4-(2-thienylcarbonyl)piperazine?
The CAS number of 1-(4-Chlorobenzyl)-4-(2-thienylcarbonyl)piperazine is 423744-78-9.
What is the molecular formula of 1-(4-Chlorobenzyl)-4-(2-thienylcarbonyl)piperazine?
The molecular formula of 1-(4-Chlorobenzyl)-4-(2-thienylcarbonyl)piperazine is C16H17ClN2OS.
What is the molecular weight of 1-(4-Chlorobenzyl)-4-(2-thienylcarbonyl)piperazine?
The molecular weight of 1-(4-Chlorobenzyl)-4-(2-thienylcarbonyl)piperazine is 320.07 g/mol.
Where can I buy 1-(4-Chlorobenzyl)-4-(2-thienylcarbonyl)piperazine?
You can request a quote for 1-(4-Chlorobenzyl)-4-(2-thienylcarbonyl)piperazine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(4-Chlorobenzyl)-4-(2-thienylcarbonyl)piperazine?
Yes, KEHONG BIO provides custom synthesis services for 1-(4-Chlorobenzyl)-4-(2-thienylcarbonyl)piperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.